HADHA protein (Homo sapiens) - STRING network view

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Score

HADHA

hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit (763 aa)

Predicted Functional Partners:

HADHB

0.999

ACAA2

0.999

ACAA1

0.999

ACAT1

0.998

ACAT2

0.997

ACADM

0.994

ACADVL

0.994

ACADS

0.992

ACOX1

0.989

ACOX3

0.988

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACAA1	ACADM	ENSP00000333664	ENSP00000409612	acetyl-CoA acyltransferase 1	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	0.975
ACAA1	ACADS	ENSP00000333664	ENSP00000242592	acetyl-CoA acyltransferase 1	acyl-CoA dehydrogenase, C-2 to C-3 short chain	0.969
ACAA1	ACADVL	ENSP00000333664	ENSP00000349297	acetyl-CoA acyltransferase 1	acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons	0.971
ACAA1	ACAT1	ENSP00000333664	ENSP00000265838	acetyl-CoA acyltransferase 1	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	0.924
ACAA1	ACAT2	ENSP00000333664	ENSP00000356015	acetyl-CoA acyltransferase 1	acetyl-CoA acetyltransferase 2	0.911
ACAA1	ACOX1	ENSP00000333664	ENSP00000293217	acetyl-CoA acyltransferase 1	acyl-CoA oxidase 1, palmitoyl	0.995
ACAA1	ACOX3	ENSP00000333664	ENSP00000348775	acetyl-CoA acyltransferase 1	acyl-CoA oxidase 3, pristanoyl; Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity)	0.992
ACAA1	HADHA	ENSP00000333664	ENSP00000370023	acetyl-CoA acyltransferase 1	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit	0.999
ACAA2	ACADM	ENSP00000285093	ENSP00000409612	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	0.981
ACAA2	ACADS	ENSP00000285093	ENSP00000242592	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acyl-CoA dehydrogenase, C-2 to C-3 short chain	0.975
ACAA2	ACADVL	ENSP00000285093	ENSP00000349297	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acyl-CoA dehydrogenase, very long chain; Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons	0.976
ACAA2	ACAT1	ENSP00000285093	ENSP00000265838	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	0.972
ACAA2	ACAT2	ENSP00000285093	ENSP00000356015	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acetyl-CoA acetyltransferase 2	0.908
ACAA2	ACOX1	ENSP00000285093	ENSP00000293217	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acyl-CoA oxidase 1, palmitoyl	0.976
ACAA2	ACOX3	ENSP00000285093	ENSP00000348775	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	acyl-CoA oxidase 3, pristanoyl; Oxidizes the CoA-esters of 2-methyl-branched fatty acids (By similarity)	0.973
ACAA2	HADHA	ENSP00000285093	ENSP00000370023	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit; Bifunctional subunit	0.999
ACADM	ACAA1	ENSP00000409612	ENSP00000333664	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	acetyl-CoA acyltransferase 1	0.975
ACADM	ACAA2	ENSP00000409612	ENSP00000285093	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	acetyl-CoA acyltransferase 2; Abolishes BNIP3-mediated apoptosis and mitochondrial damage	0.981
ACADM	ACAT1	ENSP00000409612	ENSP00000265838	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	acetyl-CoA acetyltransferase 1; Plays a major role in ketone body metabolism	0.966
ACADM	ACAT2	ENSP00000409612	ENSP00000356015	acyl-CoA dehydrogenase, C-4 to C-12 straight chain; This enzyme is specific for acyl chain lengths of 4 to 16	acetyl-CoA acetyltransferase 2	0.969

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