| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BSN | NLN | ENSP00000296452 | ENSP00000370372 | bassoon (presynaptic cytomatrix protein); Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses (By similarity) | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | 0.502 |
| BSN | UBC | ENSP00000296452 | ENSP00000344818 | bassoon (presynaptic cytomatrix protein); Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses (By similarity) | ubiquitin C | 0.473 |
| FPGT | NLN | ENSP00000359935 | ENSP00000370372 | fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | 0.644 |
| KNG1 | LAP3 | ENSP00000265023 | ENSP00000226299 | kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin- induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects- (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation [...] | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | 0.725 |
| KNG1 | NLN | ENSP00000265023 | ENSP00000370372 | kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin- induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects- (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation [...] | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | 0.680 |
| KNG1 | NTS | ENSP00000265023 | ENSP00000256010 | kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin- induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects- (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation [...] | neurotensin; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle | 0.974 |
| KNG1 | NTSR1 | ENSP00000265023 | ENSP00000359532 | kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin- induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects- (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation [...] | neurotensin receptor 1 (high affinity); Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol- calcium second messenger system | 0.908 |
| LAP3 | KNG1 | ENSP00000226299 | ENSP00000265023 | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin- induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects- (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation [...] | 0.725 |
| LAP3 | NLN | ENSP00000226299 | ENSP00000370372 | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | 0.725 |
| LAP3 | NTS | ENSP00000226299 | ENSP00000256010 | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | neurotensin; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle | 0.581 |
| LAP3 | UBC | ENSP00000226299 | ENSP00000344818 | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | ubiquitin C | 0.820 |
| NLN | BSN | ENSP00000370372 | ENSP00000296452 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | bassoon (presynaptic cytomatrix protein); Is thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act through binding to ERC2/CAST1. Essential in regulated neurotransmitter release from a subset of brain glutamatergic synapses. Involved in the formation of the retinal photoreceptor ribbon synapses (By similarity) | 0.502 |
| NLN | FPGT | ENSP00000370372 | ENSP00000359935 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | fucose-1-phosphate guanylyltransferase; Catalyzes the formation of GDP-L-fucose from GTP and L- fucose-1-phosphate. Functions as a salvage pathway to reutilize L- fucose arising from the turnover of glycoproteins and glycolipids | 0.644 |
| NLN | KNG1 | ENSP00000370372 | ENSP00000265023 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | kininogen 1; (1) Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin- induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects- (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation [...] | 0.680 |
| NLN | LAP3 | ENSP00000370372 | ENSP00000226299 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | leucine aminopeptidase 3; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides | 0.725 |
| NLN | NPEPL1 | ENSP00000370372 | ENSP00000348395 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | aminopeptidase-like 1 | 0.563 |
| NLN | NTS | ENSP00000370372 | ENSP00000256010 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | neurotensin; Neurotensin may play an endocrine or paracrine role in the regulation of fat metabolism. It causes contraction of smooth muscle | 0.784 |
| NLN | NTSR1 | ENSP00000370372 | ENSP00000359532 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | neurotensin receptor 1 (high affinity); Receptor for the tridecapeptide neurotensin. It is associated with G proteins that activate a phosphatidylinositol- calcium second messenger system | 0.606 |
| NLN | SNN | ENSP00000370372 | ENSP00000329287 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | stannin; Plays a role in the toxic effects of organotins | 0.544 |
| NLN | STX6 | ENSP00000370372 | ENSP00000258301 | neurolysin (metallopeptidase M3 family); Hydrolyzes oligopeptides such as neurotensin, bradykinin and dynorphin A (By similarity) | syntaxin 6; Involved in intracellular vesicle trafficking | 0.608 |
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