ADARB2 protein (Homo sapiens) - STRING network view

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ADARB2

adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA (739 aa)

Predicted Functional Partners:

DICER1

0.737

ADAT3

0.710

GSR

0.660

ADAT2

0.572

SPG7

0.571

GRIA2

0.550

CDA

0.546

HTR2C

0.531

GRIK2

0.497

ANKHD1

0.496

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADARB2	ADAT2	ENSP00000370713	ENSP00000237283	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity)	0.572
ADARB2	ADAT3	ENSP00000370713	ENSP00000332448	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	adenosine deaminase, tRNA-specific 3	0.710
ADARB2	ANKHD1	ENSP00000370713	ENSP00000297183	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	ankyrin repeat and KH domain containing 1	0.496
ADARB2	CDA	ENSP00000370713	ENSP00000364212	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis	0.546
ADARB2	DICER1	ENSP00000370713	ENSP00000343745	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	dicer 1, ribonuclease type III; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, EIF2C2/AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre- miRNAs) to mature miRNAs and then load them onto EIF2C2/AGO2. EIF2C2/AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. Also cleaves double-stranded RNA to produce short interfering [...]	0.737
ADARB2	GRIA2	ENSP00000370713	ENSP00000264426	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	glutamate receptor, ionotropic, AMPA 2; Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L- glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized [...]	0.550
ADARB2	GRIK2	ENSP00000370713	ENSP00000397026	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	glutamate receptor, ionotropic, kainate 2	0.497
ADARB2	GSR	ENSP00000370713	ENSP00000221130	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	glutathione reductase; Maintains high levels of reduced glutathione in the cytosol	0.660
ADARB2	HTR2C	ENSP00000370713	ENSP00000276198	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system	0.531
ADARB2	SPG7	ENSP00000370713	ENSP00000268704	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	spastic paraplegia 7 (pure and complicated autosomal recessive); Putative ATP-dependent zinc metalloprotease	0.571
ADAT2	ADARB2	ENSP00000237283	ENSP00000370713	adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity)	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	0.572
ADAT2	ADAT3	ENSP00000237283	ENSP00000332448	adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity)	adenosine deaminase, tRNA-specific 3	0.987
ADAT2	CDA	ENSP00000237283	ENSP00000364212	adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity)	cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis	0.604
ADAT3	ADARB2	ENSP00000332448	ENSP00000370713	adenosine deaminase, tRNA-specific 3	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	0.710
ADAT3	ADAT2	ENSP00000332448	ENSP00000237283	adenosine deaminase, tRNA-specific 3	adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity)	0.987
ADAT3	CDA	ENSP00000332448	ENSP00000364212	adenosine deaminase, tRNA-specific 3	cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis	0.642
ANKHD1	ADARB2	ENSP00000297183	ENSP00000370713	ankyrin repeat and KH domain containing 1	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	0.496
CDA	ADARB2	ENSP00000364212	ENSP00000370713	cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis	adenosine deaminase, RNA-specific, B2; Lacks editing activity. It prevents the binding of other ADAR enzymes to targets in vitro, and decreases the efficiency of these enzymes. Capable of binding to dsRNA but also to ssRNA	0.546
CDA	ADAT2	ENSP00000364212	ENSP00000237283	cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis	adenosine deaminase, tRNA-specific 2; Probably participates in deamination of adenosine-34 to inosine in many tRNAs (By similarity)	0.604
CDA	ADAT3	ENSP00000364212	ENSP00000332448	cytidine deaminase; This enzyme scavenge exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis	adenosine deaminase, tRNA-specific 3	0.642

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