TMEM165 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TMEM165

transmembrane protein 165 (324 aa)

Predicted Functional Partners:

UBC

0.891

MTHFD1

0.644

CALU

0.644

RPS26

0.644

RPLP1

0.644

SRD5A3

0.517

SNX31

0.492

NMU

0.483

SNX7

0.443

ALG6

0.424

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG6	SRD5A3	ENSP00000360149	ENSP00000264228	asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol	steroid 5 alpha-reductase 3; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT)	0.441
ALG6	TMEM165	ENSP00000360149	ENSP00000370736	asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol	transmembrane protein 165	0.424
CALU	TMEM165	ENSP00000420381	ENSP00000370736	calumenin	transmembrane protein 165	0.644
CALU	UBC	ENSP00000420381	ENSP00000344818	calumenin	ubiquitin C	0.731
MTHFD1	TMEM165	ENSP00000450560	ENSP00000370736	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	transmembrane protein 165	0.644
MTHFD1	UBC	ENSP00000450560	ENSP00000344818	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase	ubiquitin C	0.975
NMU	TMEM165	ENSP00000264218	ENSP00000370736	neuromedin U; Stimulates muscle contractions of specific regions of the gastrointestinal tract. In humans, NmU stimulates contractions of the ileum and urinary bladder	transmembrane protein 165	0.483
RPLP1	RPS26	ENSP00000346037	ENSP00000348849	ribosomal protein, large, P1; Plays an important role in the elongation step of protein synthesis	ribosomal protein S26	0.999
RPLP1	TMEM165	ENSP00000346037	ENSP00000370736	ribosomal protein, large, P1; Plays an important role in the elongation step of protein synthesis	transmembrane protein 165	0.644
RPLP1	UBC	ENSP00000346037	ENSP00000344818	ribosomal protein, large, P1; Plays an important role in the elongation step of protein synthesis	ubiquitin C	0.848
RPS26	RPLP1	ENSP00000348849	ENSP00000346037	ribosomal protein S26	ribosomal protein, large, P1; Plays an important role in the elongation step of protein synthesis	0.999
RPS26	TMEM165	ENSP00000348849	ENSP00000370736	ribosomal protein S26	transmembrane protein 165	0.644
RPS26	UBC	ENSP00000348849	ENSP00000344818	ribosomal protein S26	ubiquitin C	0.985
SNX31	SNX7	ENSP00000312368	ENSP00000304429	sorting nexin 31; May be involved in protein trafficking (By similarity)	sorting nexin 7	0.519
SNX31	TMEM165	ENSP00000312368	ENSP00000370736	sorting nexin 31; May be involved in protein trafficking (By similarity)	transmembrane protein 165	0.492
SNX7	SNX31	ENSP00000304429	ENSP00000312368	sorting nexin 7	sorting nexin 31; May be involved in protein trafficking (By similarity)	0.519
SNX7	TMEM165	ENSP00000304429	ENSP00000370736	sorting nexin 7	transmembrane protein 165	0.443
SRD5A3	ALG6	ENSP00000264228	ENSP00000360149	steroid 5 alpha-reductase 3; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT)	asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol	0.441
SRD5A3	TMEM165	ENSP00000264228	ENSP00000370736	steroid 5 alpha-reductase 3; Plays a key role in early steps of protein N-linked glycosylation by being required for the conversion of polyprenol into dolichol. Dolichols are required for the synthesis of dolichol-linked monosaccharides and the oligosaccharide precursor used for N-glycosylation. Acts as a polyprenol reductase that promotes the reduction of the alpha-isoprene unit of polyprenols into dolichols in a NADP-dependent mechanism. Also able to convert testosterone (T) into 5-alpha-dihydrotestosterone (DHT)	transmembrane protein 165	0.517
TMEM165	ALG6	ENSP00000370736	ENSP00000360149	transmembrane protein 165	asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae); Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol	0.424

page 1 of 2

Experiments

Cooccurrence

Databases

Neighborhood

Textmining

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About