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STRINGSTRING
ITSN1 ITSN1 EFHC2 EFHC2 NTMT1 NTMT1 ELK1 ELK1 CRYZL1 CRYZL1 ZADH2 ZADH2 NYX NYX MAOA MAOA FRMD7 FRMD7 NDP NDP MAOB MAOB
"CRYZL1" - crystallin, zeta (quinone reductase)-like 1 in Homo sapiens
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protein of unknown 3D structure
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experimentally determined
Predicted Interactions
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Score
CRYZL1crystallin, zeta (quinone reductase)-like 1 (349 aa)    
Predicted Functional Partners:
MAOA
monoamine oxidase A; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine (527 aa)
            score_image   0.777
MAOB
monoamine oxidase B; Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine (520 aa)
            score_image   0.774
NYX
nyctalopin (481 aa)
            score_image   0.756
ZADH2
zinc binding alcohol dehydrogenase domain containing 2 (377 aa)
    score_image score_image     score_image   0.755
NDP
Norrie disease (pseudoglioma); Activates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and pr [...] (133 aa)
            score_image   0.755
FRMD7
FERM domain containing 7; Plays a role in neurite development (By similarity). May play a specific role in the control of eye movement and gaze stability (714 aa)
            score_image   0.743
ITSN1
intersectin 1 (SH3 domain protein); Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR may involve association with DAB2. Isoform 1 could be involved in brain-specific synaptic vesicle recycling. Inhibits ARHGAP31 activity toward RAC1 (1721 aa)
        score_image   score_image   0.690
EFHC2
EF-hand domain (C-terminal) containing 2 (749 aa)
            score_image   0.661
ELK1
ELK1, member of ETS oncogene family; Stimulates transcription. Binds to purine-rich DNA sequences. Can form a ternary complex with the serum response factor and the ETS and SRF motifs of the fos serum response element (428 aa)
            score_image   0.661
NTMT1
N-terminal Xaa-Pro-Lys N-methyltransferase 1; Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]- Pro-Lys when the initiator Met is cleaved. Specifically catalyzes mono-, di- or tri-methylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and mono- or di- methylation of Pro in the Pro-Pro-Lys motif. Responsible for the N-terminal methylation of KLHL31, MYL2, MYL3, RB1, RCC1, RPL23A and SET. Required during mitosis for normal bipolar spindle formation and chromosome segregation vi [...] (223 aa)
        score_image       0.644
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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