node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AVL9 | NUPL1 | ENSP00000315568 | ENSP00000371155 | AVL9 homolog (S. cerevisiase); Functions in cell migration | nucleoporin like 1; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.698 |
AVL9 | RASA3 | ENSP00000315568 | ENSP00000335029 | AVL9 homolog (S. cerevisiase); Functions in cell migration | RAS p21 protein activator 3; Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4) with high affinity. Might be a specific IP4 receptor | 0.627 |
AVL9 | UBC | ENSP00000315568 | ENSP00000344818 | AVL9 homolog (S. cerevisiase); Functions in cell migration | ubiquitin C | 0.509 |
HNRNPH1 | NUPL1 | ENSP00000349168 | ENSP00000371155 | heterogeneous nuclear ribonucleoprotein H1 (H); This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) | nucleoporin like 1; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.651 |
HNRNPH1 | UBC | ENSP00000349168 | ENSP00000344818 | heterogeneous nuclear ribonucleoprotein H1 (H); This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG) | ubiquitin C | 0.995 |
ILF3 | NUPL1 | ENSP00000404121 | ENSP00000371155 | interleukin enhancer binding factor 3, 90kDa | nucleoporin like 1; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.644 |
ILF3 | UBC | ENSP00000404121 | ENSP00000344818 | interleukin enhancer binding factor 3, 90kDa | ubiquitin C | 0.969 |
LAMTOR3 | NUPL1 | ENSP00000424183 | ENSP00000371155 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances th [...] | nucleoporin like 1; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.644 |
LAMTOR3 | TOMM40 | ENSP00000424183 | ENSP00000252487 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances th [...] | translocase of outer mitochondrial membrane 40 homolog (yeast); Channel-forming protein essential for import of protein precursors into mitochondria (By similarity) | 0.590 |
LAMTOR3 | UBC | ENSP00000424183 | ENSP00000344818 | late endosomal/lysosomal adaptor, MAPK and MTOR activator 3; As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. Adapter protein that enhances th [...] | ubiquitin C | 0.483 |
NUP155 | NUP54 | ENSP00000231498 | ENSP00000264883 | nucleoporin 155kDa; Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport (By similarity) | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.968 |
NUP155 | NUP62 | ENSP00000231498 | ENSP00000305503 | nucleoporin 155kDa; Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport (By similarity) | nucleoporin 62kDa; Essential component of the nuclear pore complex. The N- terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex | 0.973 |
NUP155 | NUPL1 | ENSP00000231498 | ENSP00000371155 | nucleoporin 155kDa; Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport (By similarity) | nucleoporin like 1; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.678 |
NUP155 | UBC | ENSP00000231498 | ENSP00000344818 | nucleoporin 155kDa; Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport (By similarity) | ubiquitin C | 0.987 |
NUP54 | NUP155 | ENSP00000264883 | ENSP00000231498 | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | nucleoporin 155kDa; Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport (By similarity) | 0.968 |
NUP54 | NUP62 | ENSP00000264883 | ENSP00000305503 | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | nucleoporin 62kDa; Essential component of the nuclear pore complex. The N- terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex | 0.999 |
NUP54 | NUPL1 | ENSP00000264883 | ENSP00000371155 | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | nucleoporin like 1; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.955 |
NUP54 | UBC | ENSP00000264883 | ENSP00000344818 | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | ubiquitin C | 0.952 |
NUP62 | NUP155 | ENSP00000305503 | ENSP00000231498 | nucleoporin 62kDa; Essential component of the nuclear pore complex. The N- terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex | nucleoporin 155kDa; Essential component of nuclear pore complex. Nucleoporins may be involved both in binding and translocating proteins during nucleocytoplasmic transport (By similarity) | 0.973 |
NUP62 | NUP54 | ENSP00000305503 | ENSP00000264883 | nucleoporin 62kDa; Essential component of the nuclear pore complex. The N- terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex | nucleoporin 54kDa; Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane (By similarity) | 0.999 |