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IMP4 IMP4 BMS1 BMS1 NOP14 NOP14 DHX37 DHX37 RRP9 RRP9 NOC4L NOC4L BYSL BYSL RCL1 RCL1 UTP20 UTP20 WDR12 WDR12 TSR1 TSR1
"RCL1" - RNA terminal phosphate cyclase-like 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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experimentally determined
Predicted Interactions
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fusion edge
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textmining
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protein homology
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RCL1RNA terminal phosphate cyclase-like 1; Does not have cyclase activity. Plays a role in 40S- ribosomal-subunit biogenesis in the early pre-rRNA processing steps at sites A0, A1 and A2 that are required for proper maturation of the 18S RNA (By similarity) (373 aa)    
Predicted Functional Partners:
BMS1
BMS1 homolog, ribosome assembly protein (yeast); May act as a molecular switch during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) (1282 aa)
      score_image score_image   score_image   0.997
UTP20
UTP20, small subunit (SSU) processome component, homolog (yeast); Involved in 18S pre-rRNA processing. Associates with U3 snoRNA (2785 aa)
      score_image score_image   score_image   0.985
BYSL
bystin-like; Required for processing of 20S pre-rRNA precursor and biogenesis of 40S ribosomal subunits. May be required for trophinin-dependent regulation of cell adhesion during implantation of human embryos (437 aa)
      score_image score_image   score_image   0.980
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast); Component of a nucleolar small nuclear ribonucleoprotein particle (snoRNP) thought to participate in the processing and modification of pre-ribosomal RNA (475 aa)
      score_image score_image   score_image   0.974
DHX37
DEAH (Asp-Glu-Ala-His) box polypeptide 37 (1157 aa)
      score_image score_image   score_image   0.973
NOP14
NOP14 nucleolar protein homolog (yeast); Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity) (857 aa)
      score_image score_image   score_image   0.973
NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae) (516 aa)
      score_image score_image   score_image   0.966
IMP4
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast); Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (291 aa)
      score_image     score_image   0.965
TSR1
TSR1, 20S rRNA accumulation, homolog (S. cerevisiae); Required during maturation of the 40S ribosomal subunit in the nucleolus (By similarity) (804 aa)
      score_image     score_image   0.956
WDR12
WD repeat domain 12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome (423 aa)
      score_image     score_image   0.954
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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