LCORL protein (Homo sapiens) - STRING network view

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Score

LCORL

ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity) (602 aa)

Predicted Functional Partners:

NCAPG

0.771

FAM184B

0.669

POU4F1

0.642

POU4F2

0.642

POU4F3

0.642

C10orf12

0.602

CTBP1

0.599

DCAF16

0.584

TAPT1

0.568

ZFAT

0.517

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf12	LCORL	ENSP00000286067	ENSP00000371661	chromosome 10 open reading frame 12	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	0.602
CTBP1	LCORL	ENSP00000290921	ENSP00000371661	C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	0.599
DCAF16	FAM184B	ENSP00000371682	ENSP00000265018	DDB1 and CUL4 associated factor 16; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	family with sequence similarity 184, member B	0.616
DCAF16	LCORL	ENSP00000371682	ENSP00000371661	DDB1 and CUL4 associated factor 16; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	0.584
FAM184B	DCAF16	ENSP00000265018	ENSP00000371682	family with sequence similarity 184, member B	DDB1 and CUL4 associated factor 16; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	0.616
FAM184B	LCORL	ENSP00000265018	ENSP00000371661	family with sequence similarity 184, member B	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	0.669
LCORL	C10orf12	ENSP00000371661	ENSP00000286067	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	chromosome 10 open reading frame 12	0.602
LCORL	CTBP1	ENSP00000371661	ENSP00000290921	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity	0.599
LCORL	DCAF16	ENSP00000371661	ENSP00000371682	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	DDB1 and CUL4 associated factor 16; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex	0.584
LCORL	FAM184B	ENSP00000371661	ENSP00000265018	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	family with sequence similarity 184, member B	0.669
LCORL	NCAPG	ENSP00000371661	ENSP00000251496	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	non-SMC condensin I complex, subunit G; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases	0.771
LCORL	POU4F1	ENSP00000371661	ENSP00000366413	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	POU class 4 homeobox 1; Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons	0.642
LCORL	POU4F2	ENSP00000371661	ENSP00000281321	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	POU class 4 homeobox 2; Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons	0.642
LCORL	POU4F3	ENSP00000371661	ENSP00000230732	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	POU class 4 homeobox 3; May play a role in determining or maintaining the identities of a small subset of visual system neurons	0.642
LCORL	TAPT1	ENSP00000371661	ENSP00000385347	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	transmembrane anterior posterior transformation 1; May act as a downstream effector of HOXC8 possibly by transducing or transmitting extracellular information required for axial skeletal patterning during development (By similarity). In case of infection, may act as a fusion receptor for cytomegalovirus (HCMV) strain AD169	0.568
LCORL	ZFAT	ENSP00000371661	ENSP00000367069	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	zinc finger and AT hook domain containing	0.517
NCAPG	LCORL	ENSP00000251496	ENSP00000371661	non-SMC condensin I complex, subunit G; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	0.771
NCAPG	ZFAT	ENSP00000251496	ENSP00000367069	non-SMC condensin I complex, subunit G; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases	zinc finger and AT hook domain containing	0.488
POU4F1	LCORL	ENSP00000366413	ENSP00000371661	POU class 4 homeobox 1; Probable transcription factor which may play a role in the regulation of specific gene expression within a subset of neuronal lineages. May play a role in determining or maintaining the identities of a small subset of visual system neurons	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	0.642
POU4F2	LCORL	ENSP00000281321	ENSP00000371661	POU class 4 homeobox 2; Transcription factor. May play a role in determining or maintaining the identities of a small subset of visual system neurons	ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity)	0.642

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