| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARL3 | RP1L1 | ENSP00000260746 | ENSP00000371923 | ADP-ribosylation factor-like 3; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase- activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into [...] | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | 0.584 |
| C8orf74 | ENSG00000258724 | ENSP00000307129 | ENSP00000451145 | chromosome 8 open reading frame 74 | Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7 | 0.480 |
| C8orf74 | RP1L1 | ENSP00000307129 | ENSP00000371923 | chromosome 8 open reading frame 74 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | 0.533 |
| CERKL | RP1L1 | ENSP00000341159 | ENSP00000371923 | ceramide kinase-like | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | 0.530 |
| CERKL | ZNF513 | ENSP00000341159 | ENSP00000318373 | ceramide kinase-like | zinc finger protein 513; Transcriptional regulator that plays a role in retinal development and maintenance | 0.558 |
| DCLK3 | RP1L1 | ENSP00000394484 | ENSP00000371923 | doublecortin-like kinase 3 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | 0.656 |
| ENSG00000258724 | C8orf74 | ENSP00000451145 | ENSP00000307129 | Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7 | chromosome 8 open reading frame 74 | 0.480 |
| ENSG00000258724 | RP1L1 | ENSP00000451145 | ENSP00000371923 | Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | 0.756 |
| FRMD7 | RP1L1 | ENSP00000298542 | ENSP00000371923 | FERM domain containing 7; Plays a role in neurite development (By similarity). May play a specific role in the control of eye movement and gaze stability | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | 0.547 |
| GNAT2 | RP1L1 | ENSP00000251337 | ENSP00000371923 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | 0.513 |
| GNAT2 | ZNF513 | ENSP00000251337 | ENSP00000318373 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase | zinc finger protein 513; Transcriptional regulator that plays a role in retinal development and maintenance | 0.494 |
| RP1L1 | ARL3 | ENSP00000371923 | ENSP00000260746 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | ADP-ribosylation factor-like 3; Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase- activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into [...] | 0.584 |
| RP1L1 | C8orf74 | ENSP00000371923 | ENSP00000307129 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | chromosome 8 open reading frame 74 | 0.533 |
| RP1L1 | CERKL | ENSP00000371923 | ENSP00000341159 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | ceramide kinase-like | 0.530 |
| RP1L1 | DCLK3 | ENSP00000371923 | ENSP00000394484 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | doublecortin-like kinase 3 | 0.656 |
| RP1L1 | ENSG00000258724 | ENSP00000371923 | ENSP00000451145 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | Transcription factor SOX-7; Uncharacterized protein; cDNA FLJ58508, highly similar to Transcription factor SOX-7 | 0.756 |
| RP1L1 | FRMD7 | ENSP00000371923 | ENSP00000298542 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | FERM domain containing 7; Plays a role in neurite development (By similarity). May play a specific role in the control of eye movement and gaze stability | 0.547 |
| RP1L1 | GNAT2 | ENSP00000371923 | ENSP00000251337 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase | 0.513 |
| RP1L1 | SFXN5 | ENSP00000371923 | ENSP00000272433 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | sideroflexin 5; Transports citrate. Potential iron transporter (By similarity) | 0.505 |
| RP1L1 | SOX7 | ENSP00000371923 | ENSP00000301921 | retinitis pigmentosa 1-like 1; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors (By similarity) | SRY (sex determining region Y)-box 7; Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors (By similarity). May be required for the survival of both hematopoietic and endothelial precursors during specification (By similarity). Competes with GATA4 for binding and activation of the FGF3 promoter (By similarity). Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence [...] | 0.860 |
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