| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AMD1 | ATP6V0A2 | ENSP00000357880 | ENSP00000332247 | adenosylmethionine decarboxylase 1 | ATPase, H+ transporting, lysosomal V0 subunit a2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH | 0.405 |
| AMD1 | CLCN7 | ENSP00000357880 | ENSP00000372193 | adenosylmethionine decarboxylase 1 | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | 0.754 |
| AMD1 | OSTM1 | ENSP00000357880 | ENSP00000193322 | adenosylmethionine decarboxylase 1 | osteopetrosis associated transmembrane protein 1; Required for osteoclast and melanocyte maturation and function (By similarity) | 0.758 |
| AMD1 | UBC | ENSP00000357880 | ENSP00000344818 | adenosylmethionine decarboxylase 1 | ubiquitin C | 0.626 |
| ATP12A | ATP4A | ENSP00000218548 | ENSP00000262623 | ATPase, H+/K+ transporting, nongastric, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | 0.903 |
| ATP12A | ATP6V0A2 | ENSP00000218548 | ENSP00000332247 | ATPase, H+/K+ transporting, nongastric, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues | ATPase, H+ transporting, lysosomal V0 subunit a2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH | 0.770 |
| ATP12A | CLCN7 | ENSP00000218548 | ENSP00000372193 | ATPase, H+/K+ transporting, nongastric, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | 0.644 |
| ATP12A | OSTM1 | ENSP00000218548 | ENSP00000193322 | ATPase, H+/K+ transporting, nongastric, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues | osteopetrosis associated transmembrane protein 1; Required for osteoclast and melanocyte maturation and function (By similarity) | 0.439 |
| ATP12A | PLEKHM1 | ENSP00000218548 | ENSP00000389913 | ATPase, H+/K+ transporting, nongastric, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues | pleckstrin homology domain containing, family M (with RUN domain) member 1; Involved in vesicular transport in the osteoclast (By similarity). May have a role in sialyl-lex-mediated transduction of apoptotic signals | 0.487 |
| ATP12A | TCIRG1 | ENSP00000218548 | ENSP00000265686 | ATPase, H+/K+ transporting, nongastric, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3; Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation | 0.953 |
| ATP12A | UBC | ENSP00000218548 | ENSP00000344818 | ATPase, H+/K+ transporting, nongastric, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues | ubiquitin C | 0.937 |
| ATP4A | ATP12A | ENSP00000262623 | ENSP00000218548 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | ATPase, H+/K+ transporting, nongastric, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for potassium absorption in various tissues | 0.903 |
| ATP4A | ATP6V0A2 | ENSP00000262623 | ENSP00000332247 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | ATPase, H+ transporting, lysosomal V0 subunit a2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH | 0.774 |
| ATP4A | CLCN7 | ENSP00000262623 | ENSP00000372193 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | chloride channel, voltage-sensitive 7; Slowly voltage-gated channel mediating the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the lysosome lumen | 0.644 |
| ATP4A | LRP5 | ENSP00000262623 | ENSP00000294304 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | low density lipoprotein receptor-related protein 5; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor- ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3- mediated phosphorylation and destruction o [...] | 0.404 |
| ATP4A | OSTM1 | ENSP00000262623 | ENSP00000193322 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | osteopetrosis associated transmembrane protein 1; Required for osteoclast and melanocyte maturation and function (By similarity) | 0.440 |
| ATP4A | PLEKHM1 | ENSP00000262623 | ENSP00000389913 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | pleckstrin homology domain containing, family M (with RUN domain) member 1; Involved in vesicular transport in the osteoclast (By similarity). May have a role in sialyl-lex-mediated transduction of apoptotic signals | 0.510 |
| ATP4A | TCIRG1 | ENSP00000262623 | ENSP00000265686 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3; Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation | 0.953 |
| ATP4A | UBC | ENSP00000262623 | ENSP00000344818 | ATPase, H+/K+ exchanging, alpha polypeptide; Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach | ubiquitin C | 0.692 |
| ATP6V0A2 | AMD1 | ENSP00000332247 | ENSP00000357880 | ATPase, H+ transporting, lysosomal V0 subunit a2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH | adenosylmethionine decarboxylase 1 | 0.405 |
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