Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
|
Your Input:
|
Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
|||||
 | FLG2 | filaggrin family member 2 (2391 aa) | ||||||||||||
Predicted Functional Partners:
| ||||||||||||||
 | FAS | Fas (TNF receptor superfamily, member 6) (335 aa) |
 |
0.801 | ||||||||||
 | LCE5A | late cornified envelope 5A; Precursors of the cornified envelope of the stratum corneum (118 aa) |
|
0.585 | ||||||||||
 | ENSG00000258588 | TRIM6-TRIM34 readthrough (842 aa) |
|
0.504 | ||||||||||
 | TRIM34 | tripartite motif containing 34 (488 aa) |
|
0.455 | ||||||||||
 | LCE3A | late cornified envelope 3A; Precursors of the cornified envelope of the stratum corneum (89 aa) |
|
0.450 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
Share
