FAM83H protein (Homo sapiens) - STRING network view

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FAM83H

family with sequence similarity 83, member H; May play a major role in the structural organization and calcification of developing enamel (1179 aa)

Predicted Functional Partners:

WDR72

0.865

MMP20

0.630

DLX3

0.585

ENAM

0.582

C4orf26

0.568

AMELX

0.566

AMBN

0.507

PNPLA1

0.504

KLK4

0.502

WDR7

0.488

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AMBN	AMELX	ENSP00000313809	ENSP00000370088	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	0.811
AMBN	C4orf26	ENSP00000313809	ENSP00000406925	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	chromosome 4 open reading frame 26; Might promote nucleation of hydroxyapatite	0.406
AMBN	ENAM	ENSP00000313809	ENSP00000379383	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation	0.901
AMBN	FAM83H	ENSP00000313809	ENSP00000373565	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	family with sequence similarity 83, member H; May play a major role in the structural organization and calcification of developing enamel	0.507
AMBN	KLK4	ENSP00000313809	ENSP00000326159	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	kallikrein-related peptidase 4; Involved in enamel formation	0.700
AMBN	MMP20	ENSP00000313809	ENSP00000260228	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	matrix metallopeptidase 20; Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix- aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation	0.870
AMBN	WDR72	ENSP00000313809	ENSP00000353699	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	WD repeat domain 72	0.503
AMELX	AMBN	ENSP00000370088	ENSP00000313809	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	0.811
AMELX	C4orf26	ENSP00000370088	ENSP00000406925	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	chromosome 4 open reading frame 26; Might promote nucleation of hydroxyapatite	0.503
AMELX	DLX3	ENSP00000370088	ENSP00000389870	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	distal-less homeobox 3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis	0.418
AMELX	ENAM	ENSP00000370088	ENSP00000379383	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation	0.861
AMELX	FAM83H	ENSP00000370088	ENSP00000373565	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	family with sequence similarity 83, member H; May play a major role in the structural organization and calcification of developing enamel	0.566
AMELX	KLK4	ENSP00000370088	ENSP00000326159	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	kallikrein-related peptidase 4; Involved in enamel formation	0.567
AMELX	MMP20	ENSP00000370088	ENSP00000260228	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	matrix metallopeptidase 20; Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix- aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation	0.724
AMELX	WDR72	ENSP00000370088	ENSP00000353699	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	WD repeat domain 72	0.583
C4orf26	AMBN	ENSP00000406925	ENSP00000313809	chromosome 4 open reading frame 26; Might promote nucleation of hydroxyapatite	ameloblastin (enamel matrix protein); Involved in the mineralization and structural organization of enamel	0.406
C4orf26	AMELX	ENSP00000406925	ENSP00000370088	chromosome 4 open reading frame 26; Might promote nucleation of hydroxyapatite	amelogenin, X-linked; Plays a role in biomineralization. Seems to regulate the formation of crystallites during the secretory stage of tooth enamel development. Thought to play a major role in the structural organization and mineralization of developing enamel	0.503
C4orf26	ENAM	ENSP00000406925	ENSP00000379383	chromosome 4 open reading frame 26; Might promote nucleation of hydroxyapatite	enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation	0.506
C4orf26	FAM83H	ENSP00000406925	ENSP00000373565	chromosome 4 open reading frame 26; Might promote nucleation of hydroxyapatite	family with sequence similarity 83, member H; May play a major role in the structural organization and calcification of developing enamel	0.568
C4orf26	MMP20	ENSP00000406925	ENSP00000260228	chromosome 4 open reading frame 26; Might promote nucleation of hydroxyapatite	matrix metallopeptidase 20; Degrades amelogenin, the major protein component of the enamel matrix and two of the macromolecules characterizing the cartilage extracellular matrix- aggrecan and the cartilage oligomeric matrix protein (COMP). May play a central role in tooth enamel formation	0.508

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