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SPTBN4 SPTBN4 GAD2 GAD2 PCSK2 PCSK2 INSR INSR PTPRN2 PTPRN2 PLCB1 PLCB1 MBOAT4 MBOAT4 GHRL GHRL CPT1A CPT1A GLS2 GLS2 GPR39 GPR39
"PTPRN2" - protein tyrosine phosphatase, receptor type, N polypeptide 2 in Homo sapiens
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Predicted Interactions
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PTPRN2protein tyrosine phosphatase, receptor type, N polypeptide 2; Implicated in development of nervous system and pancreatic endocrine cells (1015 aa)    
Predicted Functional Partners:
GHRL
ghrelin/obestatin prepropeptide; Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation (117 aa)
            score_image   0.929
INSR
insulin receptor; Receptor tyrosine kinase which mediates the pleiotropic actions of insulin. Binding of insulin leads to phosphorylation of several intracellular substrates, including, insulin receptor substrates (IRS1, 2, 3, 4), SHC, GAB1, CBL and other signaling intermediates. Each of these phosphorylated proteins serve as docking proteins for other signaling proteins that contain Src- homology-2 domains (SH2 domain) that specifically recognize different phosphotyrosines residues, including the p85 regulatory subunit of PI3K and SHP2. Phosphorylation of IRSs proteins lead to the act [...] (1382 aa)
        score_image   score_image   0.836
SPTBN4
spectrin, beta, non-erythrocytic 4 (2564 aa)
        score_image   score_image   0.827
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa); Catalyzes the production of GABA (585 aa)
            score_image   0.625
PCSK2
proprotein convertase subtilisin/kexin type 2 (638 aa)
      score_image     score_image   0.617
MBOAT4
membrane bound O-acyltransferase domain containing 4; Mediates the octanoylation of ghrelin at ’Ser-3’. Can use a variety of fatty acids as substrates including octanoic acid, decanoic acid and tetradecanoic acid (435 aa)
            score_image   0.606
GLS2
glutaminase 2 (liver, mitochondrial); Plays an important role in the regulation of glutamine catabolism. Promotes mitochondrial respiration and increases ATP generation in cells by catalyzing the synthesis of glutamate and alpha-ketoglutarate. Increases cellular anti-oxidant function via NADH and glutathione production. May play a role in preventing tumor proliferation (602 aa)
            score_image   0.606
GPR39
G protein-coupled receptor 39; Zn(2+) acts as a agonist. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated mainly through G(q)-alpha and G(12)/G(13) proteins. Involved in regulation of body weight, gastrointestinal mobility, hormone secretion and cell death (By similarity) (453 aa)
            score_image   0.561
CPT1A
carnitine palmitoyltransferase 1A (liver); Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism (773 aa)
            score_image   0.517
PLCB1
phospholipase C, beta 1 (phosphoinositide-specific) (1216 aa)
            score_image   0.513
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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