CCDC57 protein (Homo sapiens) - STRING network view

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CCDC57

coiled-coil domain containing 57 (916 aa)

Predicted Functional Partners:

C19orf35

0.822

PER1

0.692

NUMA1

0.667

CNRIP1

0.533

RBM43

0.513

XKR6

0.499

SYCP2L

0.499

SLC16A3

0.475

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C19orf35	CCDC57	ENSP00000345102	ENSP00000374292	chromosome 19 open reading frame 35	coiled-coil domain containing 57	0.822
C19orf35	CNRIP1	ENSP00000345102	ENSP00000263655	chromosome 19 open reading frame 35	cannabinoid receptor interacting protein 1; Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect	0.634
C19orf35	XKR6	ENSP00000345102	ENSP00000416707	chromosome 19 open reading frame 35	XK, Kell blood group complex subunit-related family, member 6	0.563
CCDC57	C19orf35	ENSP00000374292	ENSP00000345102	coiled-coil domain containing 57	chromosome 19 open reading frame 35	0.822
CCDC57	CNRIP1	ENSP00000374292	ENSP00000263655	coiled-coil domain containing 57	cannabinoid receptor interacting protein 1; Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect	0.533
CCDC57	NUMA1	ENSP00000374292	ENSP00000377298	coiled-coil domain containing 57	nuclear mitotic apparatus protein 1; Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions	0.667
CCDC57	PER1	ENSP00000374292	ENSP00000314420	coiled-coil domain containing 57	period homolog 1 (Drosophila); Component of the circadian clock mechanism which is essential for generating circadian rhythms. Negative element in the circadian transcriptional loop. Influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. Negatively regulates CLOCK\|NPAS2-BMAL1\|BMAL2-induced transactivation. Can bind heme (By similarity)	0.692
CCDC57	RBM43	ENSP00000374292	ENSP00000331211	coiled-coil domain containing 57	RNA binding motif protein 43	0.513
CCDC57	SLC16A3	ENSP00000374292	ENSP00000376150	coiled-coil domain containing 57	solute carrier family 16, member 3 (monocarboxylic acid transporter 4); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity)	0.475
CCDC57	SYCP2L	ENSP00000374292	ENSP00000283141	coiled-coil domain containing 57	synaptonemal complex protein 2-like	0.499
CCDC57	XKR6	ENSP00000374292	ENSP00000416707	coiled-coil domain containing 57	XK, Kell blood group complex subunit-related family, member 6	0.499
CNRIP1	C19orf35	ENSP00000263655	ENSP00000345102	cannabinoid receptor interacting protein 1; Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect	chromosome 19 open reading frame 35	0.634
CNRIP1	CCDC57	ENSP00000263655	ENSP00000374292	cannabinoid receptor interacting protein 1; Isoform 1 suppresses cannabinoid receptor CNR1-mediated tonic inhibition of voltage-gated calcium channels. Isoform 2 does not have this effect	coiled-coil domain containing 57	0.533
NUMA1	CCDC57	ENSP00000377298	ENSP00000374292	nuclear mitotic apparatus protein 1; Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions	coiled-coil domain containing 57	0.667
PER1	CCDC57	ENSP00000314420	ENSP00000374292	period homolog 1 (Drosophila); Component of the circadian clock mechanism which is essential for generating circadian rhythms. Negative element in the circadian transcriptional loop. Influences clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. Negatively regulates CLOCK\|NPAS2-BMAL1\|BMAL2-induced transactivation. Can bind heme (By similarity)	coiled-coil domain containing 57	0.692
RBM43	CCDC57	ENSP00000331211	ENSP00000374292	RNA binding motif protein 43	coiled-coil domain containing 57	0.513
RBM43	SYCP2L	ENSP00000331211	ENSP00000283141	RNA binding motif protein 43	synaptonemal complex protein 2-like	0.420
SLC16A3	CCDC57	ENSP00000376150	ENSP00000374292	solute carrier family 16, member 3 (monocarboxylic acid transporter 4); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity)	coiled-coil domain containing 57	0.475
SYCP2L	CCDC57	ENSP00000283141	ENSP00000374292	synaptonemal complex protein 2-like	coiled-coil domain containing 57	0.499
SYCP2L	RBM43	ENSP00000283141	ENSP00000331211	synaptonemal complex protein 2-like	RNA binding motif protein 43	0.420

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