HAGHL protein (Homo sapiens) - STRING network view

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Score

HAGHL

hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential) (282 aa)

Predicted Functional Partners:

GLO1

0.915

LDHD

0.905

CSNK2A1

0.789

MCEE

0.560

TXNRD3

0.545

ENSG00000203546

0.461

DTD1

0.461

HDDC3

0.461

DTD2

0.461

TXNRD1

0.459

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSNK2A1	DTD1	ENSP00000217244	ENSP00000366672	casein kinase 2, alpha 1 polypeptide; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly che [...]	D-tyrosyl-tRNA deacylase 1; Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)	0.564
CSNK2A1	HAGHL	ENSP00000217244	ENSP00000374353	casein kinase 2, alpha 1 polypeptide; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly che [...]	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	0.789
DTD1	CSNK2A1	ENSP00000366672	ENSP00000217244	D-tyrosyl-tRNA deacylase 1; Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)	casein kinase 2, alpha 1 polypeptide; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly che [...]	0.564
DTD1	DTD2	ENSP00000366672	ENSP00000312224	D-tyrosyl-tRNA deacylase 1; Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)	D-tyrosyl-tRNA deacylase 2 (putative); Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential)	0.734
DTD1	HAGHL	ENSP00000366672	ENSP00000374353	D-tyrosyl-tRNA deacylase 1; Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	0.461
DTD1	HDDC3	ENSP00000366672	ENSP00000330721	D-tyrosyl-tRNA deacylase 1; Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)	HD domain containing 3; ppGpp hydrolyzing enzyme involved in starvation response	0.526
DTD2	DTD1	ENSP00000312224	ENSP00000366672	D-tyrosyl-tRNA deacylase 2 (putative); Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential)	D-tyrosyl-tRNA deacylase 1; Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)	0.734
DTD2	HAGHL	ENSP00000312224	ENSP00000374353	D-tyrosyl-tRNA deacylase 2 (putative); Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential)	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	0.461
DTD2	HDDC3	ENSP00000312224	ENSP00000330721	D-tyrosyl-tRNA deacylase 2 (putative); Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential)	HD domain containing 3; ppGpp hydrolyzing enzyme involved in starvation response	0.526
ENSG00000203546	HAGHL	ENSP00000446654	ENSP00000374353	Uncharacterized protein	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	0.461
ENSG00000203546	HDDC3	ENSP00000446654	ENSP00000330721	Uncharacterized protein	HD domain containing 3; ppGpp hydrolyzing enzyme involved in starvation response	0.526
GLO1	HAGHL	ENSP00000362463	ENSP00000374353	glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF- kappa-B	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	0.915
HAGHL	CSNK2A1	ENSP00000374353	ENSP00000217244	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	casein kinase 2, alpha 1 polypeptide; Catalytic subunit of a constitutively active serine/threonine-protein kinase complex that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine. Regulates numerous cellular processes, such as cell cycle progression, apoptosis and transcription, as well as viral infection. May act as a regulatory node which integrates and coordinates numerous signals leading to an appropriate cellular response. During mitosis, functions as a component of the p53/TP53-dependent spindle assembly che [...]	0.789
HAGHL	DTD1	ENSP00000374353	ENSP00000366672	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	D-tyrosyl-tRNA deacylase 1; Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)	0.461
HAGHL	DTD2	ENSP00000374353	ENSP00000312224	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	D-tyrosyl-tRNA deacylase 2 (putative); Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (Potential)	0.461
HAGHL	ENSG00000203546	ENSP00000374353	ENSP00000446654	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	Uncharacterized protein	0.461
HAGHL	GLO1	ENSP00000374353	ENSP00000362463	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	glyoxalase I; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF- kappa-B	0.915
HAGHL	HDDC3	ENSP00000374353	ENSP00000330721	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	HD domain containing 3; ppGpp hydrolyzing enzyme involved in starvation response	0.461
HAGHL	LDHD	ENSP00000374353	ENSP00000300051	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	lactate dehydrogenase D	0.905
HAGHL	MCEE	ENSP00000374353	ENSP00000244217	hydroxyacylglutathione hydrolase-like; Hydrolase acting on ester bonds (Potential)	methylmalonyl CoA epimerase	0.560

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