TMEM87A protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

TMEM87A

transmembrane protein 87A (555 aa)

Predicted Functional Partners:

UBC

0.868

TMEM17

0.682

DRAM2

0.668

WDR77

0.657

COG6

0.587

GPR161

0.583

LTB4R2

0.545

FAM71E1

0.534

C11orf87

0.511

GPR107

0.506

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C11orf87	DRAM2	ENSP00000331581	ENSP00000286692	chromosome 11 open reading frame 87	DNA-damage regulated autophagy modulator 2; Induces apoptotic cell death when coexpressed with DRAM1	0.414
C11orf87	TMEM17	ENSP00000331581	ENSP00000335094	chromosome 11 open reading frame 87	transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)	0.472
C11orf87	TMEM87A	ENSP00000331581	ENSP00000374484	chromosome 11 open reading frame 87	transmembrane protein 87A	0.511
COG6	TMEM17	ENSP00000397441	ENSP00000335094	component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity)	transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)	0.485
COG6	TMEM87A	ENSP00000397441	ENSP00000374484	component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity)	transmembrane protein 87A	0.587
DRAM2	C11orf87	ENSP00000286692	ENSP00000331581	DNA-damage regulated autophagy modulator 2; Induces apoptotic cell death when coexpressed with DRAM1	chromosome 11 open reading frame 87	0.414
DRAM2	TMEM17	ENSP00000286692	ENSP00000335094	DNA-damage regulated autophagy modulator 2; Induces apoptotic cell death when coexpressed with DRAM1	transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)	0.576
DRAM2	TMEM87A	ENSP00000286692	ENSP00000374484	DNA-damage regulated autophagy modulator 2; Induces apoptotic cell death when coexpressed with DRAM1	transmembrane protein 87A	0.668
FAM71E1	TMEM87A	ENSP00000270620	ENSP00000374484	family with sequence similarity 71, member E1	transmembrane protein 87A	0.534
GPR107	TMEM87A	ENSP00000361483	ENSP00000374484	G protein-coupled receptor 107	transmembrane protein 87A	0.506
GPR161	TMEM87A	ENSP00000271357	ENSP00000374484	G protein-coupled receptor 161	transmembrane protein 87A	0.583
LTB4R2	TMEM87A	ENSP00000433290	ENSP00000374484	leukotriene B4 receptor 2; Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3	transmembrane protein 87A	0.545
TMEM17	C11orf87	ENSP00000335094	ENSP00000331581	transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)	chromosome 11 open reading frame 87	0.472
TMEM17	COG6	ENSP00000335094	ENSP00000397441	transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)	component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity)	0.485
TMEM17	DRAM2	ENSP00000335094	ENSP00000286692	transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)	DNA-damage regulated autophagy modulator 2; Induces apoptotic cell death when coexpressed with DRAM1	0.576
TMEM17	TMEM87A	ENSP00000335094	ENSP00000374484	transmembrane protein 17; Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity)	transmembrane protein 87A	0.682
TMEM87A	C11orf87	ENSP00000374484	ENSP00000331581	transmembrane protein 87A	chromosome 11 open reading frame 87	0.511
TMEM87A	COG6	ENSP00000374484	ENSP00000397441	transmembrane protein 87A	component of oligomeric golgi complex 6; Required for normal Golgi function (By similarity)	0.587
TMEM87A	DRAM2	ENSP00000374484	ENSP00000286692	transmembrane protein 87A	DNA-damage regulated autophagy modulator 2; Induces apoptotic cell death when coexpressed with DRAM1	0.668
TMEM87A	FAM71E1	ENSP00000374484	ENSP00000270620	transmembrane protein 87A	family with sequence similarity 71, member E1	0.534

page 1 of 2

Experiments

Cooccurrence

Textmining

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About