node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COL12A1 | COL13A1 | ENSP00000325146 | ENSP00000381949 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XIII, alpha 1 | 0.918 |
COL12A1 | COL15A1 | ENSP00000325146 | ENSP00000364140 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle | 0.940 |
COL12A1 | COL20A1 | ENSP00000325146 | ENSP00000351767 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XX, alpha 1; Probable collagen protein | 0.904 |
COL12A1 | COL23A1 | ENSP00000325146 | ENSP00000375069 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XXIII, alpha 1 | 0.910 |
COL12A1 | COL25A1 | ENSP00000325146 | ENSP00000382083 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XXV, alpha 1; Inhibits fibrillization of beta amyloid peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin | 0.917 |
COL12A1 | COL27A1 | ENSP00000325146 | ENSP00000348385 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type XXVII, alpha 1; Plays a role during the calcification of cartilage and the transition of cartilage to bone | 0.906 |
COL12A1 | COL4A5 | ENSP00000325146 | ENSP00000331902 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type IV, alpha 5; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | 0.929 |
COL12A1 | COL8A1 | ENSP00000325146 | ENSP00000261037 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type VIII, alpha 1; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis | 0.943 |
COL12A1 | COL9A2 | ENSP00000325146 | ENSP00000361834 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | collagen, type IX, alpha 2; Structural component of hyaline cartilage and vitreous of the eye | 0.932 |
COL13A1 | COL12A1 | ENSP00000381949 | ENSP00000325146 | collagen, type XIII, alpha 1 | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | 0.918 |
COL13A1 | COL15A1 | ENSP00000381949 | ENSP00000364140 | collagen, type XIII, alpha 1 | collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle | 0.910 |
COL13A1 | COL20A1 | ENSP00000381949 | ENSP00000351767 | collagen, type XIII, alpha 1 | collagen, type XX, alpha 1; Probable collagen protein | 0.923 |
COL13A1 | COL23A1 | ENSP00000381949 | ENSP00000375069 | collagen, type XIII, alpha 1 | collagen, type XXIII, alpha 1 | 0.931 |
COL13A1 | COL25A1 | ENSP00000381949 | ENSP00000382083 | collagen, type XIII, alpha 1 | collagen, type XXV, alpha 1; Inhibits fibrillization of beta amyloid peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin | 0.924 |
COL13A1 | COL27A1 | ENSP00000381949 | ENSP00000348385 | collagen, type XIII, alpha 1 | collagen, type XXVII, alpha 1; Plays a role during the calcification of cartilage and the transition of cartilage to bone | 0.905 |
COL13A1 | COL4A5 | ENSP00000381949 | ENSP00000331902 | collagen, type XIII, alpha 1 | collagen, type IV, alpha 5; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen | 0.913 |
COL13A1 | COL8A1 | ENSP00000381949 | ENSP00000261037 | collagen, type XIII, alpha 1 | collagen, type VIII, alpha 1; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis | 0.905 |
COL13A1 | COL9A2 | ENSP00000381949 | ENSP00000361834 | collagen, type XIII, alpha 1 | collagen, type IX, alpha 2; Structural component of hyaline cartilage and vitreous of the eye | 0.905 |
COL15A1 | COL12A1 | ENSP00000364140 | ENSP00000325146 | collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle | collagen, type XII, alpha 1; Type XII collagen interacts with type I collagen- containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix (By similarity) | 0.940 |
COL15A1 | COL13A1 | ENSP00000364140 | ENSP00000381949 | collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle | collagen, type XIII, alpha 1 | 0.910 |