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STRINGSTRING
UBQLN1 UBQLN1 C8orf59 C8orf59 UBC UBC WDR73 WDR73 FAM127B FAM127B RHBDD2 RHBDD2 C17orf80 C17orf80 TMEM222 TMEM222
"FAM127B" - family with sequence similarity 127, member B in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FAM127Bfamily with sequence similarity 127, member B (113 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.922
RHBDD2
rhomboid domain containing 2 (364 aa)
            score_image   0.503
C8orf59
chromosome 8 open reading frame 59 (98 aa)
            score_image   0.476
TMEM222
transmembrane protein 222 (208 aa)
            score_image   0.472
WDR73
WD repeat domain 73 (378 aa)
            score_image   0.450
C17orf80
chromosome 17 open reading frame 80 (609 aa)
            score_image   0.412
UBQLN1
ubiquilin 1; Links CD47 to the cytoskeleton. Promotes the surface expression of GABA-A receptors (By similarity). Promotes the accumulation of uncleaved PSEN1 and PSEN2 by stimulating their biosynthesis. Has no effect on PSEN1 and PSEN2 degradation (589 aa)
        score_image       0.412
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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