node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FBXL19 | ZNF121 | ENSP00000369666 | ENSP00000326967 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 121; May be involved in transcriptional regulation | 0.501 |
FBXL19 | ZNF266 | ENSP00000369666 | ENSP00000354680 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 266; May be involved in transcriptional regulation | 0.501 |
FBXL19 | ZNF321P | ENSP00000369666 | ENSP00000375656 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 321, pseudogene | 0.501 |
FBXL19 | ZNF460 | ENSP00000369666 | ENSP00000353491 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 460; May be involved in transcriptional regulation | 0.501 |
FBXL19 | ZNF700 | ENSP00000369666 | ENSP00000254321 | F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) | zinc finger protein 700; May be involved in transcriptional regulation | 0.501 |
KDM2A | ZNF121 | ENSP00000432786 | ENSP00000326967 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 121; May be involved in transcriptional regulation | 0.501 |
KDM2A | ZNF266 | ENSP00000432786 | ENSP00000354680 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 266; May be involved in transcriptional regulation | 0.501 |
KDM2A | ZNF321P | ENSP00000432786 | ENSP00000375656 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 321, pseudogene | 0.501 |
KDM2A | ZNF460 | ENSP00000432786 | ENSP00000353491 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 460; May be involved in transcriptional regulation | 0.501 |
KDM2A | ZNF700 | ENSP00000432786 | ENSP00000254321 | lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] | zinc finger protein 700; May be involved in transcriptional regulation | 0.501 |
KDM2B | ZNF121 | ENSP00000366271 | ENSP00000326967 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger protein 121; May be involved in transcriptional regulation | 0.501 |
KDM2B | ZNF266 | ENSP00000366271 | ENSP00000354680 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger protein 266; May be involved in transcriptional regulation | 0.501 |
KDM2B | ZNF321P | ENSP00000366271 | ENSP00000375656 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger protein 321, pseudogene | 0.501 |
KDM2B | ZNF460 | ENSP00000366271 | ENSP00000353491 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger protein 460; May be involved in transcriptional regulation | 0.501 |
KDM2B | ZNF700 | ENSP00000366271 | ENSP00000254321 | lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] | zinc finger protein 700; May be involved in transcriptional regulation | 0.501 |
PTPN23 | ZNF121 | ENSP00000265562 | ENSP00000326967 | protein tyrosine phosphatase, non-receptor type 23; May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis | zinc finger protein 121; May be involved in transcriptional regulation | 0.476 |
PTPN23 | ZNF266 | ENSP00000265562 | ENSP00000354680 | protein tyrosine phosphatase, non-receptor type 23; May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis | zinc finger protein 266; May be involved in transcriptional regulation | 0.476 |
PTPN23 | ZNF321P | ENSP00000265562 | ENSP00000375656 | protein tyrosine phosphatase, non-receptor type 23; May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis | zinc finger protein 321, pseudogene | 0.476 |
PTPN23 | ZNF460 | ENSP00000265562 | ENSP00000353491 | protein tyrosine phosphatase, non-receptor type 23; May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis | zinc finger protein 460; May be involved in transcriptional regulation | 0.476 |
PTPN23 | ZNF700 | ENSP00000265562 | ENSP00000254321 | protein tyrosine phosphatase, non-receptor type 23; May act as a negative regulator of Ras-mediated mitogenic activity. Plays a role in ciliogenesis | zinc finger protein 700; May be involved in transcriptional regulation | 0.476 |