C19orf12 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

C19orf12

chromosome 19 open reading frame 12 (152 aa)

Predicted Functional Partners:

TMA16

0.569

PANK2

0.563

WDR45

0.472

PLA2G6

0.414

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C19orf12	PANK2	ENSP00000376103	ENSP00000313377	chromosome 19 open reading frame 12	pantothenate kinase 2	0.563
C19orf12	PLA2G6	ENSP00000376103	ENSP00000333142	chromosome 19 open reading frame 12	phospholipase A2, group VI (cytosolic, calcium-independent); Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pse [...]	0.414
C19orf12	TMA16	ENSP00000376103	ENSP00000351380	chromosome 19 open reading frame 12	translation machinery associated 16 homolog (S. cerevisiae)	0.569
C19orf12	WDR45	ENSP00000376103	ENSP00000348848	chromosome 19 open reading frame 12	WD repeat domain 45	0.472
PANK2	C19orf12	ENSP00000313377	ENSP00000376103	pantothenate kinase 2	chromosome 19 open reading frame 12	0.563
PANK2	PLA2G6	ENSP00000313377	ENSP00000333142	pantothenate kinase 2	phospholipase A2, group VI (cytosolic, calcium-independent); Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pse [...]	0.758
PANK2	WDR45	ENSP00000313377	ENSP00000348848	pantothenate kinase 2	WD repeat domain 45	0.427
PLA2G6	C19orf12	ENSP00000333142	ENSP00000376103	phospholipase A2, group VI (cytosolic, calcium-independent); Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pse [...]	chromosome 19 open reading frame 12	0.414
PLA2G6	PANK2	ENSP00000333142	ENSP00000313377	phospholipase A2, group VI (cytosolic, calcium-independent); Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F- actin polymerization at the pse [...]	pantothenate kinase 2	0.758
TMA16	C19orf12	ENSP00000351380	ENSP00000376103	translation machinery associated 16 homolog (S. cerevisiae)	chromosome 19 open reading frame 12	0.569
WDR45	C19orf12	ENSP00000348848	ENSP00000376103	WD repeat domain 45	chromosome 19 open reading frame 12	0.472
WDR45	PANK2	ENSP00000348848	ENSP00000313377	WD repeat domain 45	pantothenate kinase 2	0.427

Textmining

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About