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STRINGSTRING
FAM82B FAM82B KBTBD10 KBTBD10 UBC UBC STK36 STK36 ADHFE1 ADHFE1 ARMC6 ARMC6 WDR6 WDR6 ZADH2 ZADH2 SYTL3 SYTL3 QPCTL QPCTL ZMIZ1 ZMIZ1
"ARMC6" - armadillo repeat containing 6 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
ARMC6armadillo repeat containing 6 (501 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.970
SYTL3
synaptotagmin-like 3; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids in the presence of calcium ions (By similarity) (610 aa)
            score_image   0.636
WDR6
WD repeat domain 6; Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy (1151 aa)
            score_image   0.632
ADHFE1
alcohol dehydrogenase, iron containing, 1; Catalyzes the cofactor-independent reversible oxidation of gamma-hydroxybutyrate (GHB) to succinic semialdehyde (SSA) coupled to reduction of 2-ketoglutarate (2-KG) to D-2- hydroxyglutarate (D-2-HG). D,L-3-hydroxyisobutyrate and L-3- hydroxybutyrate (L-3-OHB) are also substrates for HOT with 10-fold lower activities (467 aa)
            score_image   0.621
QPCTL
glutaminyl-peptide cyclotransferase-like; Responsible for the biosynthesis of pyroglutamyl peptides (382 aa)
            score_image   0.579
KBTBD10
kelch repeat and BTB (POZ) domain containing 10; Involved in skeletal muscle development and differentiation. Regulates proliferation and differentiation of myoblasts and plays a role in myofibril assembly by promoting lateral fusion of adjacent thin fibrils into mature, wide myofibrils. Required for pseudopod elongation in transformed cells (By similarity) (606 aa)
            score_image   0.562
ZMIZ1
zinc finger, MIZ-type containing 1; Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation (1067 aa)
            score_image   0.533
ZADH2
zinc binding alcohol dehydrogenase domain containing 2 (377 aa)
            score_image   0.520
FAM82B
family with sequence similarity 82, member B (314 aa)
            score_image   0.485
STK36
serine/threonine kinase 36; Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of cerebral [...] (1315 aa)
        score_image       0.482
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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