node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASH1L | BRD1 | ENSP00000376204 | ENSP00000216267 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | bromodomain containing 1; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | 0.814 |
ASH1L | BRPF3 | ENSP00000376204 | ENSP00000350267 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | bromodomain and PHD finger containing, 3; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | 0.814 |
ASH1L | GON4L | ENSP00000376204 | ENSP00000271883 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | gon-4-like (C. elegans) | 0.865 |
ASH1L | H3F3A | ENSP00000376204 | ENSP00000355778 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | H3 histone, family 3A; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a centra [...] | 0.821 |
ASH1L | HIST1H3A | ENSP00000376204 | ENSP00000350275 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | histone cluster 1, H3a | 0.932 |
ASH1L | PLOD1 | ENSP00000376204 | ENSP00000196061 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links | 0.900 |
ASH1L | PLOD2 | ENSP00000376204 | ENSP00000282903 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links | 0.900 |
ASH1L | PLOD3 | ENSP00000376204 | ENSP00000223127 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3; Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links | 0.900 |
ASH1L | SMARCA2 | ENSP00000376204 | ENSP00000265773 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chrom [...] | 0.851 |
ASH1L | YY1AP1 | ENSP00000376204 | ENSP00000357323 | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | YY1 associated protein 1 | 0.866 |
BRD1 | ASH1L | ENSP00000216267 | ENSP00000376204 | bromodomain containing 1; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | 0.814 |
BRD1 | BRPF3 | ENSP00000216267 | ENSP00000350267 | bromodomain containing 1; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | bromodomain and PHD finger containing, 3; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | 0.946 |
BRD1 | H3F3A | ENSP00000216267 | ENSP00000355778 | bromodomain containing 1; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | H3 histone, family 3A; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a centra [...] | 0.756 |
BRD1 | HIST1H3A | ENSP00000216267 | ENSP00000350275 | bromodomain containing 1; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | histone cluster 1, H3a | 0.439 |
BRD1 | SMARCA2 | ENSP00000216267 | ENSP00000265773 | bromodomain containing 1; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chrom [...] | 0.717 |
BRPF3 | ASH1L | ENSP00000350267 | ENSP00000376204 | bromodomain and PHD finger containing, 3; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | ash1 (absent, small, or homeotic)-like (Drosophila); Histone methyltransferase specifically methylating ’Lys- 36’ of histone H3 (H3K36me) | 0.814 |
BRPF3 | BRD1 | ENSP00000350267 | ENSP00000216267 | bromodomain and PHD finger containing, 3; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | bromodomain containing 1; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | 0.946 |
BRPF3 | H3F3A | ENSP00000350267 | ENSP00000355778 | bromodomain and PHD finger containing, 3; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | H3 histone, family 3A; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a centra [...] | 0.439 |
BRPF3 | HIST1H3A | ENSP00000350267 | ENSP00000350275 | bromodomain and PHD finger containing, 3; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | histone cluster 1, H3a | 0.439 |
BRPF3 | SMARCA2 | ENSP00000350267 | ENSP00000265773 | bromodomain and PHD finger containing, 3; Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chrom [...] | 0.709 |