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STRINGSTRING
RIMS1 RIMS1 TRAPPC6A TRAPPC6A UNC13A UNC13A SYTL5 SYTL5 RAB37 RAB37 RABGGTB RABGGTB RAB5A RAB5A ARRDC3 ARRDC3 FNDC3A FNDC3A UBC UBC ARRDC4 ARRDC4
RAB37, member RAS oncogene family in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
RAB37RAB37, member RAS oncogene family (228 aa)    
Predicted Functional Partners:
UNC13A
unc-13 homolog A (C. elegans); Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-dependent refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in most excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity). Also involved in secretory granule priming in insulin secretion (By similarity). Interacts with FBXO45 (via SRY domain); [...] (1703 aa)
            score_image   0.815
RAB5A
RAB5A, member RAS oncogene family; Required for the fusion of plasma membranes and early endosomes. Contributes to the regulation of filopodia extension (215 aa)
    score_image   score_image   score_image score_image 0.631
RABGGTB
Rab geranylgeranyltransferase, beta subunit; Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively (331 aa)
        score_image       0.603
RIMS1
regulating synaptic membrane exocytosis 1 (1692 aa)
        score_image   score_image   0.574
SYTL5
synaptotagmin-like 5; May act as Rab effector protein and play a role in vesicle trafficking. Binds phospholipids (752 aa)
            score_image   0.504
UBC
ubiquitin C (685 aa)
        score_image       0.490
ARRDC3
arrestin domain containing 3 (414 aa)
            score_image   0.482
FNDC3A
fibronectin type III domain containing 3A (1198 aa)
            score_image   0.476
ARRDC4
arrestin domain containing 4 (418 aa)
            score_image   0.474
TRAPPC6A
trafficking protein particle complex 6A; May play a role in vesicular transport during the biogenesis of melanosomes (By similarity) (173 aa)
            score_image   0.463
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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