| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| DOCK1 | NTN1 | ENSP00000280333 | ENSP00000173229 | dedicator of cytokinesis 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | netrin 1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis | 0.934 |
| DOCK1 | SDK2 | ENSP00000280333 | ENSP00000376421 | dedicator of cytokinesis 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | 0.457 |
| FAM71D | GLRX3 | ENSP00000431905 | ENSP00000330836 | family with sequence similarity 71, member D | glutaredoxin 3; Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity | 0.418 |
| FAM71D | SDK2 | ENSP00000431905 | ENSP00000376421 | family with sequence similarity 71, member D | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | 0.432 |
| FAT4 | SDK2 | ENSP00000377862 | ENSP00000376421 | FAT tumor suppressor homolog 4 (Drosophila); May function in the regulation of planar cell polarity (By similarity). Cadherins are cell-cell interaction molecules (By similarity) | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | 0.453 |
| GLRX3 | FAM71D | ENSP00000330836 | ENSP00000431905 | glutaredoxin 3; Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity | family with sequence similarity 71, member D | 0.418 |
| GLRX3 | SDK2 | ENSP00000330836 | ENSP00000376421 | glutaredoxin 3; Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | 0.594 |
| GRM6 | NYX | ENSP00000231188 | ENSP00000340328 | glutamate receptor, metabotropic 6; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | nyctalopin | 0.860 |
| GRM6 | SDK2 | ENSP00000231188 | ENSP00000376421 | glutamate receptor, metabotropic 6; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | 0.680 |
| NTN1 | DOCK1 | ENSP00000173229 | ENSP00000280333 | netrin 1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis | dedicator of cytokinesis 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | 0.934 |
| NTN1 | SDK2 | ENSP00000173229 | ENSP00000376421 | netrin 1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | 0.438 |
| NYX | GRM6 | ENSP00000340328 | ENSP00000231188 | nyctalopin | glutamate receptor, metabotropic 6; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.860 |
| NYX | SDK2 | ENSP00000340328 | ENSP00000376421 | nyctalopin | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | 0.658 |
| SDK2 | DOCK1 | ENSP00000376421 | ENSP00000280333 | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | dedicator of cytokinesis 1; Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Functions as a guanine nucleotide exchange factor (GEF), which activates Rac Rho small GTPases by exchanging bound GDP for free GTP. Its GEF activity may be enhanced by ELMO1 | 0.457 |
| SDK2 | FAM71D | ENSP00000376421 | ENSP00000431905 | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | family with sequence similarity 71, member D | 0.432 |
| SDK2 | FAT4 | ENSP00000376421 | ENSP00000377862 | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | FAT tumor suppressor homolog 4 (Drosophila); May function in the regulation of planar cell polarity (By similarity). Cadherins are cell-cell interaction molecules (By similarity) | 0.453 |
| SDK2 | GLRX3 | ENSP00000376421 | ENSP00000330836 | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | glutaredoxin 3; Critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). May play a role in regulating the function of the thioredoxin system. Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity | 0.594 |
| SDK2 | GRM6 | ENSP00000376421 | ENSP00000231188 | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | glutamate receptor, metabotropic 6; Receptor for glutamate. The activity of this receptor is mediated by a G-protein that inhibits adenylate cyclase activity | 0.680 |
| SDK2 | NTN1 | ENSP00000376421 | ENSP00000173229 | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | netrin 1; Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis | 0.438 |
| SDK2 | NYX | ENSP00000376421 | ENSP00000340328 | sidekick cell adhesion molecule 2; Cell adhesion protein that guides axonal terminals to specific synapses in developing neurons (By similarity) | nyctalopin | 0.658 |
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