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SEC61A1 SEC61A1 ALG10B ALG10B DDOST DDOST UBC UBC MAGT1 MAGT1 STT3A STT3A TUSC3 TUSC3 RPN2 RPN2 DAD1 DAD1 RPN1 RPN1 ALG10 ALG10
"STT3A" - STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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white nodes:
second shell of interactors
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Predicted Interactions
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STT3ASTT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae); Catalytic subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). SST3A seems to be involved in co [...] (705 aa)    
Predicted Functional Partners:
RPN2
ribophorin II; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (631 aa)
      score_image score_image score_image score_image   0.997
DDOST
dolichyl-diphosphooligosaccharide--protein glycosyltransferase; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (456 aa)
      score_image score_image score_image score_image   0.997
RPN1
ribophorin I; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (607 aa)
      score_image score_image score_image score_image   0.996
DAD1
defender against cell death 1; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). Loss of the DAD1 protein triggers apoptosis (By similarity) (113 aa)
      score_image score_image score_image score_image   0.995
TUSC3
tumor suppressor candidate 3; Magnesium transporter. May be involved in N- glycosylation through its association with N-oligosaccharyl transferase (348 aa)
      score_image score_image score_image score_image   0.989
MAGT1
magnesium transporter 1; May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells (367 aa)
      score_image score_image score_image score_image   0.972
ALG10B
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog B (yeast); Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2 (473 aa)
        score_image score_image score_image   0.971
ALG10
asparagine-linked glycosylation 10, alpha-1,2-glucosyltransferase homolog (S. pombe); Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol (473 aa)
        score_image score_image score_image   0.971
UBC
ubiquitin C (685 aa)
        score_image       0.958
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae) (476 aa)
      score_image score_image   score_image   0.925
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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