node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CTTNBP2NL | FGFR1OP2 | ENSP00000271277 | ENSP00000229395 | CTTNBP2 N-terminal like | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | 0.514 |
CTTNBP2NL | MOB4 | ENSP00000271277 | ENSP00000315702 | CTTNBP2 N-terminal like | MOB family member 4, phocein; May play a role in membrane trafficking, specifically in membrane budding reactions (By similarity) | 0.999 |
CTTNBP2NL | MST4 | ENSP00000271277 | ENSP00000377867 | CTTNBP2 N-terminal like | Serine/threonine-protein kinase MST4 ; Mediator of cell growth. Modulates apoptosis | 0.999 |
CTTNBP2NL | PDCD10 | ENSP00000271277 | ENSP00000376506 | CTTNBP2 N-terminal like | programmed cell death 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and MST4 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity) | 0.999 |
CTTNBP2NL | SLMAP | ENSP00000271277 | ENSP00000295951 | CTTNBP2 N-terminal like | sarcolemma associated protein | 0.659 |
CTTNBP2NL | STK24 | ENSP00000271277 | ENSP00000365730 | CTTNBP2 N-terminal like | serine/threonine kinase 24; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress- induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase- independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on ’Thr-442’ and stimulates [...] | 0.999 |
CTTNBP2NL | STK25 | ENSP00000271277 | ENSP00000325748 | CTTNBP2 N-terminal like | serine/threonine kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration | 0.999 |
CTTNBP2NL | STK3 | ENSP00000271277 | ENSP00000390500 | CTTNBP2 N-terminal like | serine/threonine kinase 3; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, wh [...] | 0.999 |
CTTNBP2NL | STRIP1 | ENSP00000271277 | ENSP00000358810 | CTTNBP2 N-terminal like | striatin interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape | 0.999 |
CTTNBP2NL | STRN3 | ENSP00000271277 | ENSP00000350071 | CTTNBP2 N-terminal like | striatin, calmodulin binding protein 3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein | 0.999 |
FGFR1OP2 | CTTNBP2NL | ENSP00000229395 | ENSP00000271277 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | CTTNBP2 N-terminal like | 0.514 |
FGFR1OP2 | MOB4 | ENSP00000229395 | ENSP00000315702 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | MOB family member 4, phocein; May play a role in membrane trafficking, specifically in membrane budding reactions (By similarity) | 0.999 |
FGFR1OP2 | MST4 | ENSP00000229395 | ENSP00000377867 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | Serine/threonine-protein kinase MST4 ; Mediator of cell growth. Modulates apoptosis | 0.999 |
FGFR1OP2 | PDCD10 | ENSP00000229395 | ENSP00000376506 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | programmed cell death 10; Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and MST4 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity) | 0.999 |
FGFR1OP2 | SLMAP | ENSP00000229395 | ENSP00000295951 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | sarcolemma associated protein | 0.902 |
FGFR1OP2 | STK24 | ENSP00000229395 | ENSP00000365730 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | serine/threonine kinase 24; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress- induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase- independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on ’Thr-442’ and stimulates [...] | 0.999 |
FGFR1OP2 | STK25 | ENSP00000229395 | ENSP00000325748 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | serine/threonine kinase 25; Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration | 0.999 |
FGFR1OP2 | STK3 | ENSP00000229395 | ENSP00000390500 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | serine/threonine kinase 3; Stress-activated, pro-apoptotic kinase which, following caspase-cleavage, enters the nucleus and induces chromatin condensation followed by internucleosomal DNA fragmentation. Key component of the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, wh [...] | 0.999 |
FGFR1OP2 | STRIP1 | ENSP00000229395 | ENSP00000358810 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | striatin interacting protein 1; Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape | 0.999 |
FGFR1OP2 | STRN3 | ENSP00000229395 | ENSP00000350071 | FGFR1 oncogene partner 2; May be involved in wound healing pathway (By similarity) | striatin, calmodulin binding protein 3; Binds calmodulin in a calcium dependent manner. May function as scaffolding or signaling protein | 0.999 |