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STRINGSTRING
SAMD14 SAMD14 SPAST SPAST WSCD2 WSCD2 MAPT MAPT TTC30B TTC30B TTLL6 TTLL6 KIF6 KIF6 TEKT4 TEKT4 CEP41 CEP41 CCSAP CCSAP C21orf33 C21orf33
"TTLL6" - tubulin tyrosine ligase-like family, member 6 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
TTLL6tubulin tyrosine ligase-like family, member 6 (891 aa)    
Predicted Functional Partners:
CEP41
centrosomal protein 41kDa (373 aa)
            score_image   0.776
MAPT
microtubule-associated protein tau (776 aa)
        score_image   score_image   0.653
TTC30B
tetratricopeptide repeat domain 30B; Required for polyglutamylation of axonemal tubulin (By similarity). Plays a role in anterograde intraflagellar transport (IFT), the process by which cilia precursors are transported from the base of the cilium to the site of their incorporation at the tip (By similarity) (665 aa)
            score_image   0.629
CCSAP
centriole, cilia and spindle-associated protein; May play a role in embryonic development. May be required for proper cilia beating (By similarity) (270 aa)
            score_image   0.600
C21orf33
chromosome 21 open reading frame 33 (268 aa)
            score_image   0.530
SPAST
spastin; ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis. Also plays a role in axon growth and the formation of axonal branches (By similarity) (616 aa)
      score_image     score_image   0.518
KIF6
kinesin family member 6 (814 aa)
            score_image   0.513
WSCD2
WSC domain containing 2 (565 aa)
            score_image   0.503
TEKT4
tektin 4; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity) (435 aa)
      score_image     score_image   0.482
SAMD14
sterile alpha motif domain containing 14 (445 aa)
            score_image   0.472
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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