IGSF11 protein (Homo sapiens) - STRING network view

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IGSF11

immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth (431 aa)

Predicted Functional Partners:

CD28

0.963

PVRL4

0.960

BTNL2

0.654

CSF1R

0.609

CTLA4

0.576

C8B

0.416

ATP13A4

0.412

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP13A4	IGSF11	ENSP00000339182	ENSP00000377370	ATPase type 13A4	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	0.412
BTNL2	IGSF11	ENSP00000419512	ENSP00000377370	butyrophilin-like 2 (MHC class II associated)	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	0.654
C8B	IGSF11	ENSP00000360281	ENSP00000377370	complement component 8, beta polypeptide; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	0.416
CD28	CTLA4	ENSP00000324890	ENSP00000303939	CD28 molecule	cytotoxic T-lymphocyte-associated protein 4	0.918
CD28	IGSF11	ENSP00000324890	ENSP00000377370	CD28 molecule	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	0.963
CSF1R	IGSF11	ENSP00000286301	ENSP00000377370	colony stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone [...]	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	0.609
CTLA4	CD28	ENSP00000303939	ENSP00000324890	cytotoxic T-lymphocyte-associated protein 4	CD28 molecule	0.918
CTLA4	IGSF11	ENSP00000303939	ENSP00000377370	cytotoxic T-lymphocyte-associated protein 4	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	0.576
IGSF11	ATP13A4	ENSP00000377370	ENSP00000339182	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	ATPase type 13A4	0.412
IGSF11	BTNL2	ENSP00000377370	ENSP00000419512	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	butyrophilin-like 2 (MHC class II associated)	0.654
IGSF11	C8B	ENSP00000377370	ENSP00000360281	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	complement component 8, beta polypeptide; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells	0.416
IGSF11	CD28	ENSP00000377370	ENSP00000324890	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	CD28 molecule	0.963
IGSF11	CSF1R	ENSP00000377370	ENSP00000286301	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	colony stimulating factor 1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone [...]	0.609
IGSF11	CTLA4	ENSP00000377370	ENSP00000303939	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	cytotoxic T-lymphocyte-associated protein 4	0.576
IGSF11	PVRL4	ENSP00000377370	ENSP00000356991	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	poliovirus receptor-related 4; Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells	0.960
PVRL4	IGSF11	ENSP00000356991	ENSP00000377370	poliovirus receptor-related 4; Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with PVRL2/nectin-1. Does not act as receptor for alpha-herpesvirus entry into cells	immunoglobulin superfamily, member 11; Functions as a cell adhesion molecule through homophilic interaction. Stimulates cell growth	0.960

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