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HNF4A HNF4A SLCO1A2 SLCO1A2 ALB ALB SLC10A2 SLC10A2 FABP6 FABP6 SLC10A1 SLC10A1 SLCO1B1 SLCO1B1 ABCC3 ABCC3 NR1H4 NR1H4 SLCO1B3 SLCO1B3 ABCB11 ABCB11
"FABP6" - fatty acid binding protein 6, ileal in Homo sapiens
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protein of unknown 3D structure
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Predicted Interactions
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FABP6fatty acid binding protein 6, ileal; Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis (177 aa)    
Predicted Functional Partners:
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2; Plays a critical role in the sodium-dependent reabsorption of bile acids from the lumen of the small intestine. Plays a key role in cholesterol metabolism (348 aa)
      score_image   score_image score_image   0.981
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1; The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium (349 aa)
          score_image score_image   0.968
SLCO1B1
solute carrier organic anion transporter family, member 1B1; Mediates the Na(+)-independent uptake of organic anions such as pravastatin, taurocholate, methotrexate, dehydroepiandrosterone sulfate, 17-beta-glucuronosyl estradiol, estrone sulfate, prostaglandin E2, thromboxane B2, leukotriene C3, leukotriene E4, thyroxine and triiodothyronine. Involved in the clearance of bile acids and organic anions from the liver (691 aa)
          score_image score_image   0.942
NR1H4
nuclear receptor subfamily 1, group H, member 4; Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus (486 aa)
            score_image   0.941
SLCO1A2
solute carrier organic anion transporter family, member 1A2; Mediates the Na(+)-independent transport of organic anions such as sulfobromophthalein (BSP) and conjugated (taurocholate) and unconjugated (cholate) bile acids (By similarity). Selectively inhibited by the grapefruit juice component naringin (670 aa)
          score_image score_image   0.936
ABCC3
ATP-binding cassette, sub-family C (CFTR/MRP), member 3 (1527 aa)
          score_image score_image   0.933
SLCO1B3
solute carrier organic anion transporter family, member 1B3; Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver (702 aa)
          score_image score_image   0.932
ALB
albumin (609 aa)
          score_image score_image   0.928
HNF4A
hepatocyte nuclear factor 4, alpha (474 aa)
            score_image   0.798
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11; Involved in the ATP-dependent secretion of bile salts into the canaliculus of hepatocytes (1321 aa)
            score_image   0.757
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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