KRT35 protein (Homo sapiens) - STRING network view

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Score

KRT35

keratin 35 (455 aa)

Predicted Functional Partners:

USP15

0.740

AKAP13

0.663

RASL10A

0.628

MYO1G

0.562

KRTAP3-3

0.548

RAB33A

0.523

KRTAP3-2

0.512

HOXC13

0.503

RAB24

0.456

CD83

0.447

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKAP13	KRT35	ENSP00000354718	ENSP00000377558	A kinase (PRKA) anchor protein 13	keratin 35	0.663
AKAP13	MYO1G	ENSP00000354718	ENSP00000258787	A kinase (PRKA) anchor protein 13	myosin IG; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity)	0.698
CD83	KRT35	ENSP00000368450	ENSP00000377558	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	keratin 35	0.447
HOXC13	KRT35	ENSP00000243056	ENSP00000377558	homeobox C13; Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair-specific genes (By similarity)	keratin 35	0.503
KRT35	AKAP13	ENSP00000377558	ENSP00000354718	keratin 35	A kinase (PRKA) anchor protein 13	0.663
KRT35	CD83	ENSP00000377558	ENSP00000368450	keratin 35	CD83 molecule; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation	0.447
KRT35	HOXC13	ENSP00000377558	ENSP00000243056	keratin 35	homeobox C13; Transcription factor which plays a role in hair follicle differentiation. Regulates FOXQ1 expression and that of other hair-specific genes (By similarity)	0.503
KRT35	KRTAP3-2	ENSP00000377558	ENSP00000375429	keratin 35	keratin associated protein 3-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins	0.512
KRT35	KRTAP3-3	ENSP00000377558	ENSP00000375428	keratin 35	keratin associated protein 3-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins	0.548
KRT35	MYO1G	ENSP00000377558	ENSP00000258787	keratin 35	myosin IG; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity)	0.562
KRT35	RAB24	ENSP00000377558	ENSP00000304376	keratin 35	RAB24, member RAS oncogene family; May be involved in autophagy-related processes (By similarity)	0.456
KRT35	RAB33A	ENSP00000377558	ENSP00000257017	keratin 35	RAB33A, member RAS oncogene family	0.523
KRT35	RASL10A	ENSP00000377558	ENSP00000216101	keratin 35	RAS-like, family 10, member A; Potent inhibitor of cellular proliferation	0.628
KRT35	USP15	ENSP00000377558	ENSP00000258123	keratin 35	ubiquitin specific peptidase 15; Hydrolase that removes conjugated ubiquitin from target proteins and regulates various pathways such as the TGF-beta receptor signaling and NF-kappa-B pathways. Acts as a key regulator of TGF-beta receptor signaling pathway, but the precise mechanism is still unclear- according to a report, acts by promoting deubiquitination of monoubiquitinated R-SMADs (SMAD1, SMAD2 and/or SMAD3), thereby alleviating inhibition of R-SMADs and promoting activation of TGF-beta target genes (PubMed-21947082). According to another reports, regulates the TGF-beta receptor s [...]	0.740
KRTAP3-2	KRT35	ENSP00000375429	ENSP00000377558	keratin associated protein 3-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins	keratin 35	0.512
KRTAP3-3	KRT35	ENSP00000375428	ENSP00000377558	keratin associated protein 3-3; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins	keratin 35	0.548
MYO1G	AKAP13	ENSP00000258787	ENSP00000354718	myosin IG; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity)	A kinase (PRKA) anchor protein 13	0.698
MYO1G	KRT35	ENSP00000258787	ENSP00000377558	myosin IG; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments (By similarity)	keratin 35	0.562
RAB24	KRT35	ENSP00000304376	ENSP00000377558	RAB24, member RAS oncogene family; May be involved in autophagy-related processes (By similarity)	keratin 35	0.456
RAB33A	KRT35	ENSP00000257017	ENSP00000377558	RAB33A, member RAS oncogene family	keratin 35	0.523

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