node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACADS | SCOC | ENSP00000242592 | ENSP00000377751 | acyl-CoA dehydrogenase, C-2 to C-3 short chain | short coiled-coil protein | 0.595 |
ARFRP1 | ARL1 | ENSP00000326884 | ENSP00000261636 | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus | 0.603 |
ARFRP1 | SCOC | ENSP00000326884 | ENSP00000377751 | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | short coiled-coil protein | 0.519 |
ARL1 | ARFRP1 | ENSP00000261636 | ENSP00000326884 | ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | 0.603 |
ARL1 | SCOC | ENSP00000261636 | ENSP00000377751 | ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus | short coiled-coil protein | 0.588 |
DUSP3 | SCOC | ENSP00000226004 | ENSP00000377751 | dual specificity phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 | short coiled-coil protein | 0.576 |
FEZ1 | FEZ2 | ENSP00000278919 | ENSP00000368547 | fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules | fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity) | 0.486 |
FEZ1 | SCOC | ENSP00000278919 | ENSP00000377751 | fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules | short coiled-coil protein | 0.988 |
FEZ1 | UVRAG | ENSP00000278919 | ENSP00000348455 | fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules | UV radiation resistance associated | 0.619 |
FEZ2 | FEZ1 | ENSP00000368547 | ENSP00000278919 | fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity) | fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules | 0.486 |
FEZ2 | SCOC | ENSP00000368547 | ENSP00000377751 | fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity) | short coiled-coil protein | 0.927 |
MAP1LC3B | SCOC | ENSP00000268607 | ENSP00000377751 | microtubule-associated protein 1 light chain 3 beta; Involved in formation of autophagosomal vacuoles (autophagosomes) | short coiled-coil protein | 0.575 |
MAP1LC3B | UVRAG | ENSP00000268607 | ENSP00000348455 | microtubule-associated protein 1 light chain 3 beta; Involved in formation of autophagosomal vacuoles (autophagosomes) | UV radiation resistance associated | 0.529 |
PPFIA2 | SCOC | ENSP00000450337 | ENSP00000377751 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2; Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates | short coiled-coil protein | 0.504 |
SCOC | ACADS | ENSP00000377751 | ENSP00000242592 | short coiled-coil protein | acyl-CoA dehydrogenase, C-2 to C-3 short chain | 0.595 |
SCOC | ARFRP1 | ENSP00000377751 | ENSP00000326884 | short coiled-coil protein | ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events | 0.519 |
SCOC | ARL1 | ENSP00000377751 | ENSP00000261636 | short coiled-coil protein | ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus | 0.588 |
SCOC | DUSP3 | ENSP00000377751 | ENSP00000226004 | short coiled-coil protein | dual specificity phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 | 0.576 |
SCOC | FEZ1 | ENSP00000377751 | ENSP00000278919 | short coiled-coil protein | fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules | 0.988 |
SCOC | FEZ2 | ENSP00000377751 | ENSP00000368547 | short coiled-coil protein | fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity) | 0.927 |