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STRINGSTRING
PPFIA2 PPFIA2 ACADS ACADS TGOLN2 TGOLN2 MAP1LC3B MAP1LC3B DUSP3 DUSP3 SCOC SCOC UVRAG UVRAG FEZ1 FEZ1 ARL1 ARL1 FEZ2 FEZ2 ARFRP1 ARFRP1
"SCOC" - short coiled-coil protein in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
SCOCshort coiled-coil protein (159 aa)    
Predicted Functional Partners:
FEZ1
fasciculation and elongation protein zeta 1 (zygin I); May be involved in axonal outgrowth as component of the network of molecules that regulate cellular morphology and axon guidance machinery. Able to restore partial locomotion and axonal fasciculation to C.elegans unc-76 mutants in germline transformation experiments. May participate in the transport of mitochondria and other cargos along microtubules (392 aa)
        score_image   score_image   0.988
FEZ2
fasciculation and elongation protein zeta 2 (zygin II); Involved in axonal outgrowth and fasciculation (By similarity) (380 aa)
        score_image   score_image   0.927
UVRAG
UV radiation resistance associated (699 aa)
            score_image   0.646
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain (412 aa)
            score_image   0.595
TGOLN2
trans-golgi network protein 2 (453 aa)
        score_image   score_image   0.589
ARL1
ADP-ribosylation factor-like 1; GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus (181 aa)
        score_image   score_image   0.588
DUSP3
dual specificity phosphatase 3; Shows activity both for tyrosine-protein phosphate and serine-protein phosphate, but displays a strong preference toward phosphotyrosines. Specifically dephosphorylates and inactivates ERK1 and ERK2 (185 aa)
            score_image   0.576
MAP1LC3B
microtubule-associated protein 1 light chain 3 beta; Involved in formation of autophagosomal vacuoles (autophagosomes) (125 aa)
        score_image   score_image   0.575
ARFRP1
ADP-ribosylation factor related protein 1; Possibly involved in plasma membrane-related signaling events (201 aa)
            score_image   0.519
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2; Alters PTPRF cellular localization and induces PTPRF clustering. May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates (1257 aa)
            score_image   0.504
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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