NDRG4 protein (Homo sapiens) - STRING network view

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NDRG4

NDRG family member 4 (391 aa)

Predicted Functional Partners:

PTEN

0.674

ALCAM

0.665

GNB1

0.664

GNB2

0.664

GNB4

0.664

GNB3

0.664

MYCN

0.606

C2orf65

0.598

MYOM2

0.554

GMFG

0.542

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALCAM	NDRG4	ENSP00000305988	ENSP00000377823	activated leukocyte cell adhesion molecule; Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system	NDRG family member 4	0.665
C2orf65	NDRG4	ENSP00000290536	ENSP00000377823	chromosome 2 open reading frame 65; Required for meiosis I progression during spermatogenesis (By similarity)	NDRG family member 4	0.598
GMFG	MYOM2	ENSP00000472249	ENSP00000262113	glia maturation factor, gamma	myomesin 2	0.628
GMFG	NDRG4	ENSP00000472249	ENSP00000377823	glia maturation factor, gamma	NDRG family member 4	0.542
GNB1	GNB2	ENSP00000367869	ENSP00000305260	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	guanine nucleotide binding protein (G protein), beta polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.901
GNB1	GNB4	ENSP00000367869	ENSP00000232564	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.901
GNB1	NDRG4	ENSP00000367869	ENSP00000377823	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	NDRG family member 4	0.664
GNB2	GNB1	ENSP00000305260	ENSP00000367869	guanine nucleotide binding protein (G protein), beta polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.901
GNB2	GNB4	ENSP00000305260	ENSP00000232564	guanine nucleotide binding protein (G protein), beta polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.900
GNB2	NDRG4	ENSP00000305260	ENSP00000377823	guanine nucleotide binding protein (G protein), beta polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	NDRG family member 4	0.664
GNB3	NDRG4	ENSP00000229264	ENSP00000377823	guanine nucleotide binding protein (G protein), beta polypeptide 3; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	NDRG family member 4	0.664
GNB4	GNB1	ENSP00000232564	ENSP00000367869	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	guanine nucleotide binding protein (G protein), beta polypeptide 1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.901
GNB4	GNB2	ENSP00000232564	ENSP00000305260	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	guanine nucleotide binding protein (G protein), beta polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	0.900
GNB4	NDRG4	ENSP00000232564	ENSP00000377823	guanine nucleotide binding protein (G protein), beta polypeptide 4; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction	NDRG family member 4	0.664
MYCN	NDRG4	ENSP00000281043	ENSP00000377823	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian); May function as a transcription factor	NDRG family member 4	0.606
MYCN	PTEN	ENSP00000281043	ENSP00000361021	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian); May function as a transcription factor	phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase, removing the phosphate in the D3 position of the inositol ring from phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-diphosphate, phosphatidylinositol 3- phosphate and inositol 1,3,4,5-tetrakisphosphate with order of substrate preference in vitro PtdIns(3,4,5)P3 > PtdIns(3,4)P2 > PtdIns3P > Ins(1,3,4,5)P4. The lipid phosphatase activity is critical for its tumor [...]	0.921
MYOM2	GMFG	ENSP00000262113	ENSP00000472249	myomesin 2	glia maturation factor, gamma	0.628
MYOM2	NDRG4	ENSP00000262113	ENSP00000377823	myomesin 2	NDRG family member 4	0.554
NDRG4	ALCAM	ENSP00000377823	ENSP00000305988	NDRG family member 4	activated leukocyte cell adhesion molecule; Cell adhesion molecule that binds to CD6. Involved in neurite extension by neurons via heterophilic and homophilic interactions. May play a role in the binding of T- and B-cells to activated leukocytes, as well as in interactions between cells of the nervous system	0.665
NDRG4	C2orf65	ENSP00000377823	ENSP00000290536	NDRG family member 4	chromosome 2 open reading frame 65; Required for meiosis I progression during spermatogenesis (By similarity)	0.598

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