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STRINGSTRING
SERPINA4 SERPINA4 TBC1D29 TBC1D29 CIDEB CIDEB TMEM98 TMEM98 DHRS7B DHRS7B TMEM132E TMEM132E ENC1 ENC1
"TMEM98" - transmembrane protein 98 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
TMEM98transmembrane protein 98 (226 aa)    
Predicted Functional Partners:
DHRS7B
dehydrogenase/reductase (SDR family) member 7B; Putative oxidoreductase (Potential) (325 aa)
            score_image   0.579
TMEM132E
transmembrane protein 132E (984 aa)
            score_image   0.566
ENC1
ectodermal-neural cortex 1 (with BTB-like domain); Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin- mediated proteasomal degradation mechanism (589 aa)
            score_image   0.518
CIDEB
cell death-inducing DFFA-like effector b; Activates apoptosis (219 aa)
            score_image   0.506
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4; Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein (427 aa)
            score_image   0.488
TBC1D29
TBC1 domain family, member 29 (150 aa)
            score_image   0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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