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STRINGSTRING
SULT2B1 SULT2B1 ALDH1B1 ALDH1B1 ALDH7A1 ALDH7A1 ACYP2 ACYP2 ACO2 ACO2 ACSS2 ACSS2 ENSG00000257767 ENSG00000257767 ACSS1 ACSS1 ACOT12 ACOT12 ALDH9A1 ALDH9A1 ALDH3A2 ALDH3A2
"ACYP2" - acylphosphatase 2, muscle type in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ACYP2acylphosphatase 2, muscle type; Its physiological role is not yet clear (99 aa)    
Predicted Functional Partners:
ACSS2
acyl-CoA synthetase short-chain family member 2; Activates acetate so that it can be used for lipid synthesis or for energy generation (714 aa)
          score_image score_image   0.909
ALDH1B1
aldehyde dehydrogenase 1 family, member B1; ALDHs play a major role in the detoxification of alcohol-derived acetaldehyde. They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (517 aa)
          score_image score_image   0.906
ALDH3A2
aldehyde dehydrogenase 3 family, member A2; Catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acids. Active on a variety of saturated and unsaturated aliphatic aldehydes between 6 and 24 carbons in length. Responsible for conversion of the sphingosine 1-phosphate (S1P) degradation product hexadecenal to hexadecenoic acid (508 aa)
          score_image score_image   0.904
ENSG00000257767
Uncharacterized protein (245 aa)
          score_image     0.900
ALDH7A1
aldehyde dehydrogenase 7 family, member A1; Multifunctional enzyme mediating important protective effects. Metabolizes betaine aldehyde to betaine, an important cellular osmolyte and methyl donor. Protects cells from oxidative stress by metabolizing a number of lipid peroxidation-derived aldehydes. Involved in lysine catabolism (539 aa)
          score_image     0.900
ALDH9A1
aldehyde dehydrogenase 9 family, member A1; Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine. Catalyzes the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction (518 aa)
          score_image     0.900
ACSS1
acyl-CoA synthetase short-chain family member 1 (689 aa)
          score_image     0.900
ACOT12
acyl-CoA thioesterase 12; Hydrolyzes acetyl-CoA to acetate and CoA (555 aa)
          score_image     0.900
ACO2
aconitase 2, mitochondrial; Catalyzes the isomerization of citrate to isocitrate via cis-aconitate (By similarity) (780 aa)
            score_image   0.603
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1; Sulfotransferase that utilizes 3’-phospho-5’-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol (365 aa)
        score_image   score_image   0.600
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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