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SH2D3C SH2D3C TRIM71 TRIM71 BCAR3 BCAR3 THAP8 THAP8 EML3 EML3 KIF16B KIF16B TNPO3 TNPO3 UBC UBC SPATA5 SPATA5 EML1 EML1 TUBGCP6 TUBGCP6
"EML3" - echinoderm microtubule associated protein like 3 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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second shell of interactors
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Predicted Interactions
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protein homology
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Score
EML3echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) (896 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image       0.970
SH2D3C
SH2 domain containing 3C; Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity) (860 aa)
            score_image   0.630
TRIM71
tripartite motif containing 71, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating to post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development- positively reg [...] (868 aa)
            score_image   0.623
SPATA5
spermatogenesis associated 5; May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity) (893 aa)
            score_image   0.573
TUBGCP6
tubulin, gamma complex associated protein 6; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome (1819 aa)
            score_image   0.568
KIF16B
kinesin family member 16B (1392 aa)
            score_image   0.565
THAP8
THAP domain containing 8 (274 aa)
            score_image   0.508
BCAR3
breast cancer anti-estrogen resistance 3; May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins (825 aa)
            score_image   0.487
TNPO3
transportin 3; Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains (923 aa)
            score_image   0.455
EML1
echinoderm microtubule associated protein like 1; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) (834 aa)
            score_image   0.450
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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