node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BCAR3 | EML3 | ENSP00000260502 | ENSP00000378254 | breast cancer anti-estrogen resistance 3; May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | 0.487 |
BCAR3 | TRIM71 | ENSP00000260502 | ENSP00000373272 | breast cancer anti-estrogen resistance 3; May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins | tripartite motif containing 71, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating to post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development- positively reg [...] | 0.493 |
EML1 | EML3 | ENSP00000334314 | ENSP00000378254 | echinoderm microtubule associated protein like 1; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | 0.450 |
EML1 | KIF16B | ENSP00000334314 | ENSP00000384164 | echinoderm microtubule associated protein like 1; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | kinesin family member 16B | 0.534 |
EML1 | SPATA5 | ENSP00000334314 | ENSP00000274008 | echinoderm microtubule associated protein like 1; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | spermatogenesis associated 5; May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity) | 0.591 |
EML3 | BCAR3 | ENSP00000378254 | ENSP00000260502 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | breast cancer anti-estrogen resistance 3; May act as an adapter protein and couple activated growth factor receptors to a signaling pathway that regulates the proliferation in breast cancer cells. When overexpressed, it confers anti-estrogen resistance in breast cancer cell lines. May also be regulated by cellular adhesion to extracellular matrix proteins | 0.487 |
EML3 | EML1 | ENSP00000378254 | ENSP00000334314 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | echinoderm microtubule associated protein like 1; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | 0.450 |
EML3 | KIF16B | ENSP00000378254 | ENSP00000384164 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | kinesin family member 16B | 0.565 |
EML3 | SH2D3C | ENSP00000378254 | ENSP00000317817 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | SH2 domain containing 3C; Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity) | 0.630 |
EML3 | SPATA5 | ENSP00000378254 | ENSP00000274008 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | spermatogenesis associated 5; May be involved in morphological and functional mitochondrial transformations during spermatogenesis (By similarity) | 0.573 |
EML3 | THAP8 | ENSP00000378254 | ENSP00000292894 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | THAP domain containing 8 | 0.508 |
EML3 | TNPO3 | ENSP00000378254 | ENSP00000265388 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | transportin 3; Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains | 0.455 |
EML3 | TRIM71 | ENSP00000378254 | ENSP00000373272 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | tripartite motif containing 71, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating to post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development- positively reg [...] | 0.623 |
EML3 | TUBGCP6 | ENSP00000378254 | ENSP00000248846 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | tubulin, gamma complex associated protein 6; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome | 0.568 |
EML3 | UBC | ENSP00000378254 | ENSP00000344818 | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | ubiquitin C | 0.970 |
KIF16B | EML1 | ENSP00000384164 | ENSP00000334314 | kinesin family member 16B | echinoderm microtubule associated protein like 1; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | 0.534 |
KIF16B | EML3 | ENSP00000384164 | ENSP00000378254 | kinesin family member 16B | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | 0.565 |
KIF16B | UBC | ENSP00000384164 | ENSP00000344818 | kinesin family member 16B | ubiquitin C | 0.415 |
SH2D3C | EML3 | ENSP00000317817 | ENSP00000378254 | SH2 domain containing 3C; Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity) | echinoderm microtubule associated protein like 3; May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity) | 0.630 |
SH2D3C | TRIM71 | ENSP00000317817 | ENSP00000373272 | SH2 domain containing 3C; Eph receptor-binding protein which may be a positive regulator of TCR signaling. Binding to BCAR1 is required to induce membrane ruffling and promote EGF-dependent cell migration (By similarity) | tripartite motif containing 71, E3 ubiquitin protein ligase; E3 ubiquitin-protein ligase that cooperates with the microRNAs (miRNAs) machinery and promotes embryonic stem cells proliferation and maintenance. Binds to miRNAs and associates with AGO2, participating to post-transcriptional repression of transcripts such as CDKN1A. Facilitates the G1-S transition to promote rapid embryonic stem cell self-renewal by repressing CDKN1A expression. Required to maintain proliferation and prevent premature differentiation of neural progenitor cells during early neural development- positively reg [...] | 0.625 |