node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALG1 | ALG13 | ENSP00000262374 | ENSP00000378260 | asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | 0.966 |
ALG1 | ALG14 | ENSP00000262374 | ENSP00000359224 | asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER | 0.978 |
ALG1 | DPAGT1 | ENSP00000262374 | ENSP00000346142 | asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase); Catalyzes the initial step in the synthesis of dolichol- P-P-oligosaccharides | 0.850 |
ALG1 | DPM1 | ENSP00000262374 | ENSP00000360644 | asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins | 0.978 |
ALG13 | ALG1 | ENSP00000378260 | ENSP00000262374 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER | 0.966 |
ALG13 | ALG14 | ENSP00000378260 | ENSP00000359224 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER | 0.999 |
ALG13 | ALG1L | ENSP00000378260 | ENSP00000340009 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | asparagine-linked glycosylation 1-like; Putative glycosyltransferase (By similarity) | 0.523 |
ALG13 | DPAGT1 | ENSP00000378260 | ENSP00000346142 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase); Catalyzes the initial step in the synthesis of dolichol- P-P-oligosaccharides | 0.977 |
ALG13 | DPM1 | ENSP00000378260 | ENSP00000360644 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins | 0.534 |
ALG13 | MRPL16 | ENSP00000378260 | ENSP00000300151 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | mitochondrial ribosomal protein L16; Component of the large subunit of mitochondrial ribosome | 0.472 |
ALG13 | OTUB1 | ENSP00000378260 | ENSP00000402551 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | OTU domain, ubiquitin aldehyde binding 1; Hydrolase that can specifically remove ’Lys-48’-linked conjugated ubiquitin from proteins and plays an important regulatory role at the level of protein turnover by preventing degradation. Regulator of T-cell anergy, a phenomenon that occurs when T-cells are rendered unresponsive to antigen rechallenge and no longer respond to their cognate antigen. Acts via its interaction with RNF128/GRAIL, a crucial inductor of CD4 T-cell anergy. Isoform 1 destabilizes RNF128, leading to prevent anergy. In contrast, isoform 2 stabilizes RNF128 and promotes a [...] | 0.474 |
ALG13 | OTUB2 | ENSP00000378260 | ENSP00000203664 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | OTU domain, ubiquitin aldehyde binding 2; Hydrolase that can remove conjugated ubiquitin from proteins in vitro and may therefore play an important regulatory role at the level of protein turnover by preventing degradation. Mediates deubiquitination of both ’Lys-48’- and ’Lys-63’-linked polyubiquitin chains, with a preference for ’Lys-63’-linked polyubiquitin chains | 0.474 |
ALG13 | OTUD6A | ENSP00000378260 | ENSP00000339389 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | OTU domain containing 6A | 0.517 |
ALG13 | SAV1 | ENSP00000378260 | ENSP00000324729 | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | salvador homolog 1 (Drosophila); Regulator of STK3/MST2 and STK4/MST1 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the n [...] | 0.481 |
ALG14 | ALG1 | ENSP00000359224 | ENSP00000262374 | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER | asparagine-linked glycosylation 1, beta-1,4-mannosyltransferase homolog (S. cerevisiae); Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER | 0.978 |
ALG14 | ALG13 | ENSP00000359224 | ENSP00000378260 | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER | asparagine-linked glycosylation 13 homolog (S. cerevisiae) | 0.999 |
ALG14 | ALG1L | ENSP00000359224 | ENSP00000340009 | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER | asparagine-linked glycosylation 1-like; Putative glycosyltransferase (By similarity) | 0.567 |
ALG14 | DPAGT1 | ENSP00000359224 | ENSP00000346142 | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER | dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase); Catalyzes the initial step in the synthesis of dolichol- P-P-oligosaccharides | 0.993 |
ALG14 | DPM1 | ENSP00000359224 | ENSP00000360644 | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins | 0.602 |
ALG14 | MRPL16 | ENSP00000359224 | ENSP00000300151 | asparagine-linked glycosylation 14 homolog (S. cerevisiae); May be involved in protein N-glycosylation. May play a role in the second step of the dolichol-linked oligosaccharide pathway. May anchor the catalytic subunit ALG13 to the ER | mitochondrial ribosomal protein L16; Component of the large subunit of mitochondrial ribosome | 0.450 |