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MYL2 MYL2 CALML5 CALML5 CALM1 CALM1 CALML3 CALML3 MYLK3 MYLK3 MYH14 MYH14 MYL7 MYL7 CALML6 CALML6 MYL6 MYL6 MYL9 MYL9 MYL12B MYL12B
"MYLK3" - myosin light chain kinase 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
MYLK3myosin light chain kinase 3; Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity) (819 aa)    
Predicted Functional Partners:
MYL9
myosin, light chain 9, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (172 aa)
        score_image score_image score_image   0.987
MYL2
myosin, light chain 2, regulatory, cardiac, slow (166 aa)
        score_image score_image score_image   0.985
MYL7
myosin, light chain 7, regulatory (175 aa)
        score_image score_image score_image   0.976
MYH14
myosin, heavy chain 14, non-muscle (2036 aa)
      score_image     score_image   0.965
CALM1
calmodulin 1 (phosphorylase kinase, delta) (149 aa)
        score_image score_image score_image   0.936
MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle; Regulatory light chain of myosin. Does not bind calcium (151 aa)
        score_image score_image score_image   0.888
CALML5
calmodulin-like 5; Binds calcium. May be involved in terminal differentiation of keratinocytes (146 aa)
        score_image score_image score_image   0.879
CALML3
calmodulin-like 3; May be similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinities, to cellular substrates (149 aa)
        score_image score_image score_image   0.879
CALML6
calmodulin-like 6 (181 aa)
        score_image score_image score_image   0.879
MYL12B
myosin, light chain 12B, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Phosphorylation triggers actin polymerization in vascular smooth muscle. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity) (172 aa)
        score_image score_image score_image   0.859
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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