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STRINGSTRING
FGF8 FGF8 EN1 EN1 LBH LBH LGALS4 LGALS4 ANKRD1 ANKRD1 YPEL5 YPEL5
"LBH" - limb bud and heart development homolog in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Cooccurence
Coexpression
Experiments
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[Homology]
Score
LBHlimb bud and heart development homolog (mouse); Transcriptional activator which may act in mitogen- activated protein kinase signaling pathway (105 aa)    
Predicted Functional Partners:
EN1
engrailed homeobox 1 (392 aa)
             score_image   0.683
LGALS4
lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions (323 aa)
             score_image   0.560
FGF8
fibroblast growth factor 8 (androgen-induced); Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (244 aa)
             score_image   0.499
ANKRD1
ankyrin repeat domain 1 (cardiac muscle); May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells (319 aa)
             score_image   0.456
YPEL5
yippee-like 5 (Drosophila) (121 aa)
             score_image   0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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