node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCG2 | SLC16A9 | ENSP00000237612 | ENSP00000378756 | ATP-binding cassette, sub-family G (WHITE), member 2 | solute carrier family 16, member 9 (monocarboxylic acid transporter 9); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity) | 0.589 |
ABCG2 | SLC17A1 | ENSP00000237612 | ENSP00000244527 | ATP-binding cassette, sub-family G (WHITE), member 2 | solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane | 0.505 |
ABCG2 | SLC17A3 | ENSP00000237612 | ENSP00000380250 | ATP-binding cassette, sub-family G (WHITE), member 2 | solute carrier family 17 (sodium phosphate), member 3; Isoform 2- voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport | 0.635 |
ABCG2 | SLC22A11 | ENSP00000237612 | ENSP00000301891 | ATP-binding cassette, sub-family G (WHITE), member 2 | solute carrier family 22 (organic anion/urate transporter), member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds | 0.594 |
ABCG2 | SLC22A12 | ENSP00000237612 | ENSP00000366797 | ATP-binding cassette, sub-family G (WHITE), member 2 | solute carrier family 22 (organic anion/urate transporter), member 12; Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions | 0.551 |
ABCG2 | SLC2A9 | ENSP00000237612 | ENSP00000264784 | ATP-binding cassette, sub-family G (WHITE), member 2 | solute carrier family 2 (facilitated glucose transporter), member 9; Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate | 0.693 |
ABCG2 | UBC | ENSP00000237612 | ENSP00000344818 | ATP-binding cassette, sub-family G (WHITE), member 2 | ubiquitin C | 0.724 |
FAM188B | SLC16A9 | ENSP00000265299 | ENSP00000378756 | family with sequence similarity 188, member B | solute carrier family 16, member 9 (monocarboxylic acid transporter 9); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity) | 0.565 |
LRRC16A | PDZK1 | ENSP00000331983 | ENSP00000342143 | leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) | PDZ domain containing 1 | 0.459 |
LRRC16A | SLC16A9 | ENSP00000331983 | ENSP00000378756 | leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) | solute carrier family 16, member 9 (monocarboxylic acid transporter 9); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity) | 0.658 |
LRRC16A | SLC17A1 | ENSP00000331983 | ENSP00000244527 | leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) | solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane | 0.499 |
LRRC16A | SLC17A3 | ENSP00000331983 | ENSP00000380250 | leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) | solute carrier family 17 (sodium phosphate), member 3; Isoform 2- voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport | 0.499 |
LRRC16A | SLC22A11 | ENSP00000331983 | ENSP00000301891 | leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) | solute carrier family 22 (organic anion/urate transporter), member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds | 0.499 |
LRRC16A | SLC2A9 | ENSP00000331983 | ENSP00000264784 | leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) | solute carrier family 2 (facilitated glucose transporter), member 9; Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate | 0.565 |
LRRC16A | UBC | ENSP00000331983 | ENSP00000344818 | leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) | ubiquitin C | 0.816 |
PDZK1 | LRRC16A | ENSP00000342143 | ENSP00000331983 | PDZ domain containing 1 | leucine rich repeat containing 16A; Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization (By similarity) | 0.459 |
PDZK1 | SLC16A9 | ENSP00000342143 | ENSP00000378756 | PDZ domain containing 1 | solute carrier family 16, member 9 (monocarboxylic acid transporter 9); Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity) | 0.637 |
PDZK1 | SLC17A1 | ENSP00000342143 | ENSP00000244527 | PDZ domain containing 1 | solute carrier family 17 (sodium phosphate), member 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane | 0.596 |
PDZK1 | SLC17A3 | ENSP00000342143 | ENSP00000380250 | PDZ domain containing 1 | solute carrier family 17 (sodium phosphate), member 3; Isoform 2- voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport | 0.501 |
PDZK1 | SLC22A11 | ENSP00000342143 | ENSP00000301891 | PDZ domain containing 1 | solute carrier family 22 (organic anion/urate transporter), member 11; Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds | 0.605 |