MAPK1IP1L protein (Homo sapiens) - STRING network view

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MAPK1IP1L

mitogen-activated protein kinase 1 interacting protein 1-like (245 aa)

Predicted Functional Partners:

TFG

0.754

ALG2

0.719

PDCD6

0.705

ARHGEF16

0.649

COX19

0.508

CHCHD4

0.472

C1orf94

0.448

ATXN3

0.408

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALG2	MAPK1IP1L	ENSP00000417764	ENSP00000378851	asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate	mitogen-activated protein kinase 1 interacting protein 1-like	0.719
ALG2	PDCD6	ENSP00000417764	ENSP00000264933	asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate	programmed cell death 6; Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity	0.729
ARHGEF16	MAPK1IP1L	ENSP00000367629	ENSP00000378851	Rho guanine nucleotide exchange factor (GEF) 16; Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6	mitogen-activated protein kinase 1 interacting protein 1-like	0.649
ARHGEF16	TFG	ENSP00000367629	ENSP00000240851	Rho guanine nucleotide exchange factor (GEF) 16; Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6	TRK-fused gene	0.686
ATXN3	MAPK1IP1L	ENSP00000376965	ENSP00000378851	ataxin 3	mitogen-activated protein kinase 1 interacting protein 1-like	0.408
C1orf94	MAPK1IP1L	ENSP00000435634	ENSP00000378851	chromosome 1 open reading frame 94	mitogen-activated protein kinase 1 interacting protein 1-like	0.448
CHCHD4	COX19	ENSP00000295767	ENSP00000342015	coiled-coil-helix-coiled-coil-helix domain containing 4; Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contain [...]	cytochrome c oxidase assembly homolog 19 (S. cerevisiae); May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity)	0.967
CHCHD4	MAPK1IP1L	ENSP00000295767	ENSP00000378851	coiled-coil-helix-coiled-coil-helix domain containing 4; Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contain [...]	mitogen-activated protein kinase 1 interacting protein 1-like	0.472
COX19	CHCHD4	ENSP00000342015	ENSP00000295767	cytochrome c oxidase assembly homolog 19 (S. cerevisiae); May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity)	coiled-coil-helix-coiled-coil-helix domain containing 4; Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contain [...]	0.967
COX19	MAPK1IP1L	ENSP00000342015	ENSP00000378851	cytochrome c oxidase assembly homolog 19 (S. cerevisiae); May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity)	mitogen-activated protein kinase 1 interacting protein 1-like	0.508
MAPK1IP1L	ALG2	ENSP00000378851	ENSP00000417764	mitogen-activated protein kinase 1 interacting protein 1-like	asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate	0.719
MAPK1IP1L	ARHGEF16	ENSP00000378851	ENSP00000367629	mitogen-activated protein kinase 1 interacting protein 1-like	Rho guanine nucleotide exchange factor (GEF) 16; Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 and mediate activation of CDC42 by the viral protein HPV16 E6	0.649
MAPK1IP1L	ATXN3	ENSP00000378851	ENSP00000376965	mitogen-activated protein kinase 1 interacting protein 1-like	ataxin 3	0.408
MAPK1IP1L	C1orf94	ENSP00000378851	ENSP00000435634	mitogen-activated protein kinase 1 interacting protein 1-like	chromosome 1 open reading frame 94	0.448
MAPK1IP1L	CHCHD4	ENSP00000378851	ENSP00000295767	mitogen-activated protein kinase 1 interacting protein 1-like	coiled-coil-helix-coiled-coil-helix domain containing 4; Functions as chaperone and catalyzes the formation of disulfide bonds in substrate proteins, such as COX17. Required for the import and folding of small cysteine-containing proteins (small Tim) in the mitochondrial intermembrane space (IMS). Precursor proteins to be imported into the IMS are translocated in their reduced form into the mitochondria. The oxidized form of CHCHD4/MIA40 forms a transient intermolecular disulfide bridge with the reduced precursor protein, resulting in oxidation of the precursor protein that now contain [...]	0.472
MAPK1IP1L	COX19	ENSP00000378851	ENSP00000342015	mitogen-activated protein kinase 1 interacting protein 1-like	cytochrome c oxidase assembly homolog 19 (S. cerevisiae); May be required for the assembly of mitochondrial cytochrome c oxidase (By similarity)	0.508
MAPK1IP1L	PDCD6	ENSP00000378851	ENSP00000264933	mitogen-activated protein kinase 1 interacting protein 1-like	programmed cell death 6; Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity	0.705
MAPK1IP1L	TFG	ENSP00000378851	ENSP00000240851	mitogen-activated protein kinase 1 interacting protein 1-like	TRK-fused gene	0.754
PDCD6	ALG2	ENSP00000264933	ENSP00000417764	programmed cell death 6; Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity	asparagine-linked glycosylation 2, alpha-1,3-mannosyltransferase homolog (S. cerevisiae); Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)- dolichol diphosphate	0.729
PDCD6	MAPK1IP1L	ENSP00000264933	ENSP00000378851	programmed cell death 6; Calcium-binding protein required for T-cell receptor-, Fas-, and glucocorticoid-induced cell death. May mediate Ca(2+)- regulated signals along the death pathway (By similarity). Calcium-dependent adapter necessary for the association between PDCD6IP and TSG101. Interaction with DAPK1 can accelerate apoptotic cell death by increasing caspase-3 activity	mitogen-activated protein kinase 1 interacting protein 1-like	0.705

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