Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
DTNB DTNB DTNA DTNA UTRN UTRN ADRA1D ADRA1D DMD DMD SNTB1 SNTB1 DAG1 DAG1 SGCA SGCA SGCB SGCB SGCG SGCG SGCD SGCD
"SNTB1" - syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SNTB1syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1); Adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. May link various receptors to the actin cytoskeleton and the dystrophin glycoprotein complex (538 aa)    
Predicted Functional Partners:
DMD
dystrophin (3685 aa)
        score_image score_image score_image   0.982
UTRN
utrophin; May play a role in anchoring the cytoskeleton to the plasma membrane (By similarity) (3433 aa)
        score_image score_image score_image   0.957
DTNA
dystrobrevin, alpha (743 aa)
        score_image   score_image   0.919
SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein); Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix (290 aa)
          score_image score_image   0.902
SGCA
sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein); Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix (387 aa)
          score_image score_image   0.885
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein); Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix (291 aa)
          score_image score_image   0.864
SGCB
sarcoglycan, beta (43kDa dystrophin-associated glycoprotein); Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix (318 aa)
          score_image score_image   0.849
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1); The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sarcolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization (895 aa)
          score_image score_image   0.831
DTNB
dystrobrevin, beta (627 aa)
        score_image   score_image   0.820
ADRA1D
adrenoceptor alpha 1D; This alpha-adrenergic receptor mediates its effect through the influx of extracellular calcium (572 aa)
        score_image   score_image   0.811
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: medium (46%)