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ST3GAL1 ST3GAL1 FUT7 FUT7 ST3GAL2 ST3GAL2 ST3GAL6 ST3GAL6 FUT6 FUT6 ST8SIA1 ST8SIA1 B4GALNT1 B4GALNT1 FUT4 FUT4 ST3GAL5 ST3GAL5 HEXB HEXB HEXA HEXA
"ST8SIA1" - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 in Homo sapiens
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ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid (356 aa)    
Predicted Functional Partners:
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1; Involved in the biosynthesis of gangliosides GM2, GD2 and GA2 (533 aa)
          score_image score_image   0.977
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5; Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D- glucosylceramide) (418 aa)
          score_image score_image   0.966
ST3GAL1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1; It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O- linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values (340 aa)
          score_image score_image score_image 0.929
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (331 aa)
          score_image score_image   0.925
ST3GAL2
ST3 beta-galactoside alpha-2,3-sialyltransferase 2; It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found in terminal carbohydrate groups of certain glycoproteins, oligosaccharides and glycolipids. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values (350 aa)
          score_image score_image score_image 0.923
HEXB
hexosaminidase B (beta polypeptide); Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues (556 aa)
          score_image score_image   0.915
FUT6
fucosyltransferase 6 (alpha (1,3) fucosyltransferase); Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose to alpha-2,3 sialylated substrates (359 aa)
          score_image score_image   0.912
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase); May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens (342 aa)
          score_image score_image   0.909
FUT4
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific); May catalyze alpha-1,3 glycosidic linkages involved in the expression of Lewis X/SSEA-1 and VIM-2 antigens (530 aa)
          score_image score_image   0.909
HEXA
hexosaminidase A (alpha polypeptide); Responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. The form B is active against certain oligosaccharides. The form S has no measurable activity (529 aa)
          score_image score_image   0.908
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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