Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CNN1 | NAV2 | ENSP00000252456 | ENSP00000379394 | calponin 1, basic, smooth muscle; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity) | neuron navigator 2 | 0.681 |
GRAP | GRAP2 | ENSP00000284154 | ENSP00000339186 | GRB2-related adaptor protein; Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway | GRB2-related adaptor protein 2; Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc | 0.906 |
GRAP | NAV2 | ENSP00000284154 | ENSP00000379394 | GRB2-related adaptor protein; Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway | neuron navigator 2 | 0.727 |
GRAP2 | GRAP | ENSP00000339186 | ENSP00000284154 | GRB2-related adaptor protein 2; Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc | GRB2-related adaptor protein; Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway | 0.906 |
GRAP2 | NAV2 | ENSP00000339186 | ENSP00000379394 | GRB2-related adaptor protein 2; Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc | neuron navigator 2 | 0.674 |
GRAPL | NAV2 | ENSP00000437409 | ENSP00000379394 | GRB2-related adaptor protein-like | neuron navigator 2 | 0.674 |
GRB2 | NAV2 | ENSP00000339007 | ENSP00000379394 | growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway | neuron navigator 2 | 0.732 |
ING4 | NAV2 | ENSP00000380024 | ENSP00000379394 | inhibitor of growth family, member 4 | neuron navigator 2 | 0.587 |
LHX3 | NAV2 | ENSP00000360811 | ENSP00000379394 | LIM homeobox 3; Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1 | neuron navigator 2 | 0.701 |
LHX4 | NAV2 | ENSP00000263726 | ENSP00000379394 | LIM homeobox 4; May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung (By similarity) | neuron navigator 2 | 0.701 |
NAV2 | CNN1 | ENSP00000379394 | ENSP00000252456 | neuron navigator 2 | calponin 1, basic, smooth muscle; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity) | 0.681 |
NAV2 | GRAP | ENSP00000379394 | ENSP00000284154 | neuron navigator 2 | GRB2-related adaptor protein; Couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway | 0.727 |
NAV2 | GRAP2 | ENSP00000379394 | ENSP00000339186 | neuron navigator 2 | GRB2-related adaptor protein 2; Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc | 0.674 |
NAV2 | GRAPL | ENSP00000379394 | ENSP00000437409 | neuron navigator 2 | GRB2-related adaptor protein-like | 0.674 |
NAV2 | GRB2 | ENSP00000379394 | ENSP00000339007 | neuron navigator 2 | growth factor receptor-bound protein 2; Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway | 0.732 |
NAV2 | ING4 | ENSP00000379394 | ENSP00000380024 | neuron navigator 2 | inhibitor of growth family, member 4 | 0.587 |
NAV2 | LHX3 | ENSP00000379394 | ENSP00000360811 | neuron navigator 2 | LIM homeobox 3; Acts as a transcriptional activator. Binds to and activates the promoter of the alpha-glycoprotein gene, and synergistically enhances transcription from the prolactin promoter in cooperation with POU1F1/Pit-1 (By similarity). Required for the establishment of the specialized cells of the pituitary gland and the nervous system. Involved in the development of interneurons and motor neurons in cooperation with LDB1 and ISL1 | 0.701 |
NAV2 | LHX4 | ENSP00000379394 | ENSP00000263726 | neuron navigator 2 | LIM homeobox 4; May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung (By similarity) | 0.701 |
NAV2 | PIAS2 | ENSP00000379394 | ENSP00000465676 | neuron navigator 2 | protein inhibitor of activated STAT, 2; Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing may vary depending upon the biological context and the PIAS2 isoform studied. However, it seems to be mostly involved in gene silencing. Bin [...] | 0.623 |
NAV2 | TRIO | ENSP00000379394 | ENSP00000339299 | neuron navigator 2 | trio Rho guanine nucleotide exchange factor; Promotes the exchange of GDP by GTP. Together with leukocyte antigen-related (LAR) protein, it could play a role in coordinating cell-matrix and cytoskeletal rearrangements necessary for cell migration and cell growth | 0.610 |
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