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PYROXD2 PYROXD2 NDUFAF2 NDUFAF2 ACACB ACACB NDUFAF4 NDUFAF4 NDUFAF5 NDUFAF5 NDUFAF6 NDUFAF6 ACACA ACACA NDUFAF3 NDUFAF3 NDUFAF1 NDUFAF1 C14orf1 C14orf1 HSD17B7 HSD17B7
"NDUFAF6" - NADH dehydrogenase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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white nodes:
second shell of interactors
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experimentally determined
Predicted Interactions
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fusion edge
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gene co-occurrence
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textmining
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co-expression
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protein homology
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Score
NDUFAF6NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; Involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of MT-ND1 (333 aa)    
Predicted Functional Partners:
NDUFAF5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5; Involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I, MT-ND1) at early stages. May have methyltransferase activity (345 aa)
     score_image score_image     score_image   0.863
ACACA
acetyl-CoA carboxylase alpha (2383 aa)
         score_image   score_image   0.859
ACACB
acetyl-CoA carboxylase beta; ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions- biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase (2458 aa)
         score_image   score_image   0.859
NDUFAF1
NADH dehydrogenase (ubiquinone) complex I, assembly factor 1; Chaperone protein involved in the assembly of the mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) (By similarity) (327 aa)
       score_image     score_image   0.762
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7; Responsible for the reduction of the keto group on the C-3 of sterols (341 aa)
       score_image score_image   score_image   0.714
C14orf1
chromosome 14 open reading frame 1 (140 aa)
       score_image score_image       0.690
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3; Essential factor for the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) (184 aa)
     score_image       score_image   0.680
NDUFAF4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4; Involved in the assembly of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion (175 aa)
       score_image     score_image   0.678
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly (169 aa)
             score_image   0.658
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2; Probable oxidoreductase (By similarity) (581 aa)
 score_image     score_image     score_image   0.657
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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