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STRINGSTRING
ATAD3A ATAD3A KIAA0430 KIAA0430 LRPPRC LRPPRC FOPNL FOPNL MPV17L MPV17L C16orf45 C16orf45 ZNF205 ZNF205 MRPS26 MRPS26 MRPS18B MRPS18B
"MPV17L" - MPV17 mitochondrial membrane protein-like in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
MPV17LMPV17 mitochondrial membrane protein-like; Isoform 1 participates in reactive oxygen species metablism by up- or down-regulation of the genes of antioxidant enzymes (196 aa)    
Predicted Functional Partners:
MRPS26
mitochondrial ribosomal protein S26 (205 aa)
            score_image   0.544
C16orf45
chromosome 16 open reading frame 45 (204 aa)
            score_image   0.536
KIAA0430
KIAA0430 (1742 aa)
            score_image   0.525
ATAD3A
ATPase family, AAA domain containing 3A; Essential for mitochondrial network organization, mitochondrial metabolism and cell growth at organism and cellular level. May play an important in mitochondrial protein synthesis. May also participate in mitochondrial DNA replication. May bind to mitochondrial DNA D-loops and contribute to nucleoid stability. Required for enhanced channeling of cholesterol for hormone- dependent steroidogenesis (634 aa)
            score_image   0.485
LRPPRC
leucine-rich pentatricopeptide repeat containing; May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondria [...] (1394 aa)
            score_image   0.480
MRPS18B
mitochondrial ribosomal protein S18B (258 aa)
            score_image   0.480
FOPNL
FGFR1OP N-terminal like; Involved in the biogenesis of cilia (174 aa)
      score_image     score_image   0.473
ZNF205
zinc finger protein 205; May be involved in transcriptional regulation (554 aa)
            score_image   0.406
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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