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STRINGSTRING
FBXL19 FBXL19 NDUFAF2 NDUFAF2 KDM2A KDM2A ZNF765 ZNF765 SLC39A9 SLC39A9 UBC UBC KDM2B KDM2B DZIP3 DZIP3 C9orf153 C9orf153 GIMAP1 GIMAP1 XRN1 XRN1
"ZNF765" - zinc finger protein 765 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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Experiments
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[Homology]
Score
ZNF765zinc finger protein 765; May be involved in transcriptional regulation (By similarity) (523 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.685
GIMAP1
GTPase, IMAP family member 1; May regulate lymphocyte survival. Required for normal levels of mature T-lymphocytes and mature B-cells (By similarity) (306 aa)
            score_image   0.633
C9orf153
chromosome 9 open reading frame 153 (101 aa)
            score_image   0.562
XRN1
5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) (1706 aa)
      score_image score_image   score_image   0.543
DZIP3
DAZ interacting protein 3, zinc finger (1208 aa)
        score_image       0.543
SLC39A9
solute carrier family 39 (zinc transporter), member 9; May act as a zinc-influx transporter (By similarity) (307 aa)
            score_image   0.519
NDUFAF2
NADH dehydrogenase (ubiquinone) complex I, assembly factor 2; Acts as a molecular chaperone for mitochondrial complex I assembly (169 aa)
            score_image   0.503
KDM2A
lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] (1162 aa)
        score_image   score_image   0.501
FBXL19
F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) (694 aa)
        score_image   score_image   0.501
KDM2B
lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] (1336 aa)
        score_image   score_image   0.501
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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