COL4A4 protein (Homo sapiens) - STRING network view

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COL4A4

collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen (1690 aa)

Predicted Functional Partners:

COL4A5

0.930

COL8A2

0.929

COL4A3

0.929

COL4A2

0.923

COL4A1

0.917

COL15A1

0.915

COL7A1

0.914

ITGA2

0.912

COL1A1

0.912

COL1A2

0.911

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL15A1	COL1A1	ENSP00000364140	ENSP00000225964	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type I, alpha 1	0.923
COL15A1	COL1A2	ENSP00000364140	ENSP00000297268	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type I, alpha 2	0.923
COL15A1	COL4A1	ENSP00000364140	ENSP00000364979	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.922
COL15A1	COL4A2	ENSP00000364140	ENSP00000353654	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type IV, alpha 2; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.955
COL15A1	COL4A3	ENSP00000364140	ENSP00000379823	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type IV, alpha 3 (Goodpasture antigen)	0.924
COL15A1	COL4A4	ENSP00000364140	ENSP00000379866	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.915
COL15A1	COL4A5	ENSP00000364140	ENSP00000331902	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type IV, alpha 5; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.948
COL15A1	COL7A1	ENSP00000364140	ENSP00000332371	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type VII, alpha 1; Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen	0.915
COL15A1	COL8A2	ENSP00000364140	ENSP00000305913	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	collagen, type VIII, alpha 2; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity)	0.923
COL1A1	COL15A1	ENSP00000225964	ENSP00000364140	collagen, type I, alpha 1	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	0.923
COL1A1	COL1A2	ENSP00000225964	ENSP00000297268	collagen, type I, alpha 1	collagen, type I, alpha 2	0.963
COL1A1	COL4A1	ENSP00000225964	ENSP00000364979	collagen, type I, alpha 1	collagen, type IV, alpha 1; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.928
COL1A1	COL4A2	ENSP00000225964	ENSP00000353654	collagen, type I, alpha 1	collagen, type IV, alpha 2; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.919
COL1A1	COL4A3	ENSP00000225964	ENSP00000379823	collagen, type I, alpha 1	collagen, type IV, alpha 3 (Goodpasture antigen)	0.911
COL1A1	COL4A4	ENSP00000225964	ENSP00000379866	collagen, type I, alpha 1	collagen, type IV, alpha 4; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.912
COL1A1	COL4A5	ENSP00000225964	ENSP00000331902	collagen, type I, alpha 1	collagen, type IV, alpha 5; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a ’chicken-wire’ meshwork together with laminins, proteoglycans and entactin/nidogen	0.949
COL1A1	COL7A1	ENSP00000225964	ENSP00000332371	collagen, type I, alpha 1	collagen, type VII, alpha 1; Stratified squamous epithelial basement membrane protein that forms anchoring fibrils which may contribute to epithelial basement membrane organization and adherence by interacting with extracellular matrix (ECM) proteins such as type IV collagen	0.977
COL1A1	COL8A2	ENSP00000225964	ENSP00000305913	collagen, type I, alpha 1	collagen, type VIII, alpha 2; Macromolecular component of the subendothelium. Major component of the Descemet’s membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis (By similarity)	0.900
COL1A1	ITGA2	ENSP00000225964	ENSP00000296585	collagen, type I, alpha 1	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor); Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix	0.985
COL1A2	COL15A1	ENSP00000297268	ENSP00000364140	collagen, type I, alpha 2	collagen, type XV, alpha 1; Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle	0.923

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