node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP5J2 | MRPS34 | ENSP00000292475 | ENSP00000380531 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a [...] | mitochondrial ribosomal protein S34 | 0.661 |
ATP5J2 | UBC | ENSP00000292475 | ENSP00000344818 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a [...] | ubiquitin C | 0.495 |
DLG1 | DLG2 | ENSP00000345731 | ENSP00000365272 | discs, large homolog 1 (Drosophila) | discs, large homolog 2 (Drosophila); Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity) | 0.574 |
DLG1 | MRPS34 | ENSP00000345731 | ENSP00000380531 | discs, large homolog 1 (Drosophila) | mitochondrial ribosomal protein S34 | 0.916 |
DLG1 | UBC | ENSP00000345731 | ENSP00000344818 | discs, large homolog 1 (Drosophila) | ubiquitin C | 0.942 |
DLG2 | DLG1 | ENSP00000365272 | ENSP00000345731 | discs, large homolog 2 (Drosophila); Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity) | discs, large homolog 1 (Drosophila) | 0.574 |
DLG2 | MRPS34 | ENSP00000365272 | ENSP00000380531 | discs, large homolog 2 (Drosophila); Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity) | mitochondrial ribosomal protein S34 | 0.576 |
HNRNPU | ILF2 | ENSP00000283179 | ENSP00000355011 | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA | interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus | 0.622 |
HNRNPU | MRPL44 | ENSP00000283179 | ENSP00000258383 | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA | mitochondrial ribosomal protein L44; Component of the 39S subunit of mitochondrial ribosome | 0.603 |
HNRNPU | MRPS34 | ENSP00000283179 | ENSP00000380531 | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA | mitochondrial ribosomal protein S34 | 0.644 |
HNRNPU | UBC | ENSP00000283179 | ENSP00000344818 | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA | ubiquitin C | 0.995 |
ILF2 | HNRNPU | ENSP00000355011 | ENSP00000283179 | interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA | 0.622 |
ILF2 | MRPS34 | ENSP00000355011 | ENSP00000380531 | interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus | mitochondrial ribosomal protein S34 | 0.648 |
ILF2 | UBC | ENSP00000355011 | ENSP00000344818 | interleukin enhancer binding factor 2, 45kDa; Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus | ubiquitin C | 0.992 |
MRPL44 | HNRNPU | ENSP00000258383 | ENSP00000283179 | mitochondrial ribosomal protein L44; Component of the 39S subunit of mitochondrial ribosome | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A); Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA | 0.603 |
MRPL44 | MRPS34 | ENSP00000258383 | ENSP00000380531 | mitochondrial ribosomal protein L44; Component of the 39S subunit of mitochondrial ribosome | mitochondrial ribosomal protein S34 | 0.635 |
MRPL44 | UBC | ENSP00000258383 | ENSP00000344818 | mitochondrial ribosomal protein L44; Component of the 39S subunit of mitochondrial ribosome | ubiquitin C | 0.504 |
MRPL49 | MRPS34 | ENSP00000279242 | ENSP00000380531 | mitochondrial ribosomal protein L49 | mitochondrial ribosomal protein S34 | 0.497 |
MRPS34 | ATP5J2 | ENSP00000380531 | ENSP00000292475 | mitochondrial ribosomal protein S34 | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a [...] | 0.661 |
MRPS34 | DLG1 | ENSP00000380531 | ENSP00000345731 | mitochondrial ribosomal protein S34 | discs, large homolog 1 (Drosophila) | 0.916 |