SLC35E3 protein (Homo sapiens) - STRING network view

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Score

SLC35E3

solute carrier family 35, member E3; Putative transporter (By similarity) (313 aa)

Predicted Functional Partners:

SLC35C2

0.731

SLC35F1

0.672

SLC35C1

0.610

SLC35F2

0.503

SLC35F3

0.503

INO80

0.443

SLC35B3

0.430

NIPAL1

0.424

NUP107

0.416

SLC39A11

0.411

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
INO80	SLC35E3	ENSP00000355205	ENSP00000381089	INO80 homolog (S. cerevisiae); DNA helicase and probable main scaffold component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair; according to PubMed-20687897 the contribution to DNA double-strand break repair appears to be largely indirect through transcriptional regulation. Recruited by YY1 to YY1-activated genes, where it acts as an essential coactivator. Binds DNA. In vitro, has double stranded DNA-dependent ATPase activity. Involved in UV-damage excision repair, DNA replication and chromosome segreg [...]	solute carrier family 35, member E3; Putative transporter (By similarity)	0.443
NIPAL1	SLC35B3	ENSP00000295461	ENSP00000368981	NIPA-like domain containing 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	0.692
NIPAL1	SLC35C1	ENSP00000295461	ENSP00000313318	NIPA-like domain containing 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)	solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen	0.545
NIPAL1	SLC35C2	ENSP00000295461	ENSP00000243896	NIPA-like domain containing 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)	solute carrier family 35, member C2; May play an important role in the cellular response to tissue hypoxia	0.690
NIPAL1	SLC35E3	ENSP00000295461	ENSP00000381089	NIPA-like domain containing 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)	solute carrier family 35, member E3; Putative transporter (By similarity)	0.424
NIPAL1	SLC35F1	ENSP00000295461	ENSP00000353557	NIPA-like domain containing 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)	solute carrier family 35, member F1; Putative solute transporter (Potential)	0.683
NIPAL1	SLC39A11	ENSP00000295461	ENSP00000445829	NIPA-like domain containing 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)	solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity)	0.432
NUP107	SLC35E3	ENSP00000229179	ENSP00000381089	nucleoporin 107kDa; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. Required for the assembly of peripheral proteins into the NPC. May anchor NUP62 to the NPC	solute carrier family 35, member E3; Putative transporter (By similarity)	0.416
SLC35B3	NIPAL1	ENSP00000368981	ENSP00000295461	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	NIPA-like domain containing 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)	0.692
SLC35B3	SLC35C1	ENSP00000368981	ENSP00000313318	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen	0.765
SLC35B3	SLC35C2	ENSP00000368981	ENSP00000243896	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	solute carrier family 35, member C2; May play an important role in the cellular response to tissue hypoxia	0.672
SLC35B3	SLC35E3	ENSP00000368981	ENSP00000381089	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	solute carrier family 35, member E3; Putative transporter (By similarity)	0.430
SLC35B3	SLC35F1	ENSP00000368981	ENSP00000353557	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	solute carrier family 35, member F1; Putative solute transporter (Potential)	0.668
SLC35B3	SLC35F2	ENSP00000368981	ENSP00000393571	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	solute carrier family 35, member F2; Putative solute transporter (Potential)	0.563
SLC35B3	SLC39A11	ENSP00000368981	ENSP00000445829	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	solute carrier family 39 (metal ion transporter), member 11; May act as a zinc-influx transporter (By similarity)	0.536
SLC35C1	NIPAL1	ENSP00000313318	ENSP00000295461	solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen	NIPA-like domain containing 1; Acts as a Mg(2+) transporter. Can also transport other divalent cations such as Fe(2+), Sr(2+), Ba(2+), Mn(2+), Cu(2+) and Co(2+) but to a much less extent than Mg(2+) (By similarity)	0.545
SLC35C1	SLC35B3	ENSP00000313318	ENSP00000368981	solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen	solute carrier family 35, member B3; Mediates the transport of adenosine 3’-phospho 5’- phosphosulfate (PAPS), from cytosol into Golgi. PAPS is a universal sulfuryl donor for sulfation events that take place in the Golgi. Compensates for the insufficient expression of SLC35B2/PAPST1 during the synthesis of sulfated glycoconjugates in the colon	0.765
SLC35C1	SLC35C2	ENSP00000313318	ENSP00000243896	solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen	solute carrier family 35, member C2; May play an important role in the cellular response to tissue hypoxia	0.835
SLC35C1	SLC35E3	ENSP00000313318	ENSP00000381089	solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen	solute carrier family 35, member E3; Putative transporter (By similarity)	0.610
SLC35C1	SLC35F1	ENSP00000313318	ENSP00000353557	solute carrier family 35, member C1; Involved in GDP-fucose import from the cytoplasm into the Golgi lumen	solute carrier family 35, member F1; Putative solute transporter (Potential)	0.584

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