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TUBA1B TUBA1B DYNC1I2 DYNC1I2 DYNC2LI1 DYNC2LI1 DYNC1I1 DYNC1I1 DYNC2H1 DYNC2H1 DCTN1 DCTN1 ACTR1A ACTR1A ACTR1B ACTR1B DYNLL2 DYNLL2 DYNLL1 DYNLL1 DCTN5 DCTN5
"DYNC2H1" - dynein, cytoplasmic 2, heavy chain 1 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
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gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Score
DYNC2H1dynein, cytoplasmic 2, heavy chain 1 (4314 aa)    
Predicted Functional Partners:
DYNC2LI1
dynein, cytoplasmic 2, light intermediate chain 1 (351 aa)
        score_image score_image score_image   0.995
DYNLL1
dynein, light chain, LC8-type 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (89 aa)
        score_image score_image score_image   0.986
DYNLL2
dynein, light chain, LC8-type 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity) (89 aa)
        score_image score_image score_image   0.986
DCTN1
dynactin 1 (1278 aa)
      score_image score_image score_image score_image   0.967
DYNC1I2
dynein, cytoplasmic 1, intermediate chain 2 (638 aa)
      score_image   score_image score_image   0.964
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (376 aa)
        score_image score_image score_image   0.959
ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast); Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome (376 aa)
        score_image score_image score_image   0.959
DYNC1I1
dynein, cytoplasmic 1, intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150- glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and k [...] (645 aa)
      score_image   score_image score_image   0.955
DCTN5
dynactin 5 (p25) (182 aa)
          score_image score_image   0.946
TUBA1B
tubulin, alpha 1b; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) (451 aa)
        score_image score_image score_image   0.942
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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